CiteWeb

WorldWeb citation database

Publications in 2014

Page 3
A draft map of the human proteome

Min-Sik Kim, Sneha M. Pinto, Derese Getnet, Raja Sekhar Nirujogi, Srikanth S. Manda, Raghothama Chaerkady, Anil K. Madugundu, Dhanashree S. Kelkar, Ruth Isserlin, Shobhit Jain, Joji Kurian Thomas, Babylakshmi Muthusamy, Pamela Leal-Rojas, Praveen Kumar, Nandini A. Sahasrabuddhe, Lavanya Balakrishnan, Jayshree Advani, Bijesh George, Santosh Renuse, Lakshmi Dhevi N. Selvan, Arun H. Patil, Vishalakshi Nanjappa, Aneesha Radhakrishnan, Samarjeet Prasad, Tejaswini Subbannayya, Rajesh Raju, Manish Kumar, Sreelakshmi K Sreenivasamurthy, Arivusudar Marimuthu, Gajanan Sathe, Sandip Chavan, Keshava K. Datta, Yashwanth Subbannayya, Apeksha Sahu, Soujanya D. Yelamanchi, Savita Jayaram, P. K. Rajagopalan, Jyoti Sharma, Krishna R. Murthy, Nazia Syed, Renu Goel, Aafaque Ahmad Khan, Sartaj Ahmad, Gourav Dey, Keshav Mudgal, Aditi Chatterjee, Tai-Chung Huang, Jun Zhong, Xinyan Wu, Patrick G. Shaw

Angiotensin-neprilysin inhibition versus enalapril in heart failure.

BackgroundWe compared the angiotensin receptor–neprilysin inhibitor LCZ696 with enalapril in patients who had heart failure with a reduced ejection fraction. In previous studies, enalapril improved survival in such patients. MethodsIn this double-blind...

2014 AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Ezra A. Amsterdam, Nanette K. Wenger, Ralph G. Brindis, Donald E. Casey, Theodore G. Ganiats, David R. Holmes, Hani Jneid, Rosemary F. Kelly, Michael C. Kontos, Glenn N. Levine, Philip R. Liebson, Debabrata Mukherjee, Eric D. Peterson, Marc S. Sabatine, Richard W. Smalling, Susan J. Zieman

STRING v10: protein-protein interaction networks, integrated over the tree of life.

The many functional partnerships and interactions that occur between proteins are at the core of cellular processing and their systematic characterization helps to provide context in molecular systems biology. However, known and predicted interactions...

Strategies to Prevent Central Line-Associated Bloodstream Infections in Acute Care Hospitals: 2014 Update

Jonas Marschall, Leonard A. Mermel, Mohamad G. Fakih, Lynn Hadaway, Alexander J. Kallen, Naomi P. O’Grady, Ann Marie Pettis, Mark E. Rupp, Thomas J. Sandora, Lisa L. Maragakis, Deborah S. Yokoe

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

In the past 8 years, both the International Working Group (IWG) and the US National Institute on Aging–Alzheimer’s Association have contributed criteria for the diagnosis of Alzheimer’s disease (AD) that better define clinical phenotypes and integrate...

Multistate Point-Prevalence Survey of Health Care–Associated Infections

Background Currently, no single U.S. surveillance system can provide estimates of the burden of all types of health care–associated infections across acute care patient populations. We conducted a prevalence survey in 10 geographically diverse states...

Levels of selected carcinogens and toxicants in vapour from electronic cigarettes

Significance Electronic cigarettes, also known as ecigarettes, are devices designed to imitate regular cigarettes and deliver nicotine via inhalation without combusting tobacco. They are purported to deliver nicotine without other toxicants and to be...

2014 Evidence-based guideline for the management of high blood pressure in adults

Paul A. James, Suzanne Oparil, Barry L. Carter, William C. Cushman, Cheryl R. Dennison Himmelfarb, Joel Handler, Daniel T. Lackland, Michael L. LeFevre, Thomas D. MacKenzie, Olugbenga Ogedegbe, Sidney C. Smith, Laura P. Svetkey, Sandra J. Taler, Raymond R. Townsend, Jackson T. Wright, Andrew S. Narva, Eduardo Ortiz

Penetrating the fog: analytics in learning and education

In the era of Internet, mobile technologies and open education, the need for changes to improve the efficiency and quality of higher education has become crucial. Big data and analytics can contribute to these changes and reshape the future of higher...

2014 AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes

Preamble e3461. Introduction e3472. Overview of Acs e3493. Initial Evaluation and Management e3504. Early Hospital Care e359

REVIEW OF PARTICLE PHYSICS Particle Data Group

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,283 new measurements from 899 Japers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons,...

A Pyrrhic Victory? Bank Bailouts and Sovereign Credit Risk

type="main"> We model a loop between sovereign and bank credit risk. A distressed financial sector induces government bailouts, whose cost increases sovereign credit risk. Increased sovereign credit risk in turn weakens the financial sector by eroding...

Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Martin Reck, Sanjay Popat, N. Reinmuth, D. De Ruysscher, Keith M. Kerr, Solange Peters

2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.

Ezra A. Amsterdam, Nanette K. Wenger, Ralph G. Brindis, Donald E. Casey, Theodore G. Ganiats, David R. Holmes, Allan S. Jaffe, Hani Jneid, Rosemary F. Kelly, Michael C. Kontos, Glenn N. Levine, Philip R. Liebson, Debabrata Mukherjee, Eric D. Peterson, Marc S. Sabatine, Richard W. Smalling, Susan J. Zieman, Interventions

Examining Teachers' Beliefs about the Role of Technology in the Elementary Classroom

Although teachers today recognize the importance of integrating technology into their curricula, successful implementation often is hampered by both external (first-order) and internal (second-order) barriers. This study was designed to examine the relationship...

Curiosity's rover environmental monitoring station: Overview of the first 100 sols

Carlos Armiens, Isaías Carrasco, Maria Genzer, Felipe Gómez, Robert M. Haberle, Victoria E. Hamilton, Ari-Matti Harri, Henrik Kahanpää, Osku Kemppinen, A. Lepinette, Javier Martín Soler, Javier Martin-Torres, Michael Andrew Mischna, Luis Paulino Mora Mora, Sara M Navarro, Claire E. Newman, Miguel Angel de Pablo, V. Peinado, Jouni Polkko, Scot C. Randell Rafkin, Miguel Ramos, Nilton De Oliveira Renno, Mark Ian Richardson, J. A. Rodriguez-Manfredi, Julio J. Romeral Planelló, E. Sebastián, Manuel de la Torre Juarez, Josefina Torres, R. Urqui, Ashwin R. Vasavada, José Alexandre Alves Verdasca, María-Paz Zorzano

InterProScan 5: genome-scale protein function classification

Motivation: Robust, large-scale sequence analysis is a major challenge in modern genomic science, where biologists are frequently trying to characterise many millions of sequences. Here we describe a new Java-based architecture for the widely-used protein...

A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

Background In two of three phase 3 trials, pirfenidone, an oral antifibrotic therapy, reduced disease progression, as measured by the decline in forced vital capacity (FVC) or vital capacity, in patients with idiopathic pulmonary fibrosis; in the third...

2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism

ACS: acute coronary syndromeAMPLIFY: Apixaban for the Initial Management of Pulmonary Embolism and Deep-Vein Thrombosis as First-line TherapyaPTT: activated partial thromboplastin timeb.i.d.: bis in diem (twice daily)b.p.m.: beats per minuteBNP:...

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

The high rate of mortality in the current Ebola epidemic has made it difficult for researchers to collect samples of the virus and study its evolution. Gire et al. describe Ebola epidemiology on the basis of 99 whole-genome sequences, including samples...

Five disruptive technology directions for 5G

New research directions will lead to fundamental changes in the design of future fifth generation (5G) cellular networks. This article describes five technologies that could lead to both architectural and component disruptive design changes: device-centric...

The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST)

In 2004, the SEED (http://pubseed.theseed.org/) was created to provide consistent and accurate genome annotations across thousands of genomes and as a platform for discovering and developing de novo annotations. The SEED is a constantly updated integration...

The automated computation of tree-level and next-to-leading order differential cross sections, and their matching to parton shower simulations

We discuss the theoretical bases that underpin the automation of the computations of tree-level and next-to-leading order cross sections, of their matching to parton shower simulations, and of the merging of matched samples that differ by light-parton...

Aggregation and morphology control enables multiple cases of high-efficiency polymer solar cells

Although the field of polymer solar cell has seen much progress in device performance in the past few years, several limitations are holding back its further development. For instance, current high-efficiency (49.0%) cells are restricted...

2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC).

Perry M. Elliott, Aris Anastasakis, Michael A. Borger, Martin Borggrefe, Franco Cecchi, Charron P, Albert A. Hagège, Antoine Lafont, Giuseppe Limongelli, Heiko Mahrholdt, Wj McKenna, Jens Mogensen, Petros Nihoyannopoulos, Stefano Nistri, Petronella G. Pieper, Burkert Pieske, Claudio Rapezzi, Frans H. Rutten, Christoph Tillmanns, Hugh Watkins, Additional Contributor, C. O'Mahony, Jose Luis Zamorano, S. Achenbach, H. Baumgartner, J. J. Bax, H. Bueno, V. Dean, C. Deaton, C. Erol, R. Fagard, R. Ferrari, David Hasdai, A. W. Hoes, Paulus Kirchhof, J. Knuuti, P. Kolh, Lancellotti P, Ales Linhart, M. F. Piepoli, Piotr Ponikowski, Per Anton Sirnes, J. L. Tamargo, Michal Tendera, Adam Torbicki, W. Wijns, Stephan Windecker, Document Reviewers, F. Alfonso, Cristina Basso

Growth rate of small lung cancers detected on mass CT screening.

CT has recently been used in mass screening for lung cancer. Small cancers have been identified but the growth characteristics of these lesions are not fully understood. We identified 82 primary cancers in our 3-year mass CT screening programme, of which...

Twelve or 30 Months of Dual Antiplatelet Therapy after Drug-Eluting Stents

BackgroundDual antiplatelet therapy is recommended after coronary stenting to prevent thrombotic complications, yet the benefits and risks of treatment beyond 1 year are uncertain. MethodsPatients were enrolled after they had undergone a coronary stent...

Celebrity and power : fame in contemporary culture

Through a new introduction for this edition, Marshall investigates the viewing public's desire to associate with celebrity and addresses the explosion of instant access to celebrity culture, bringing famous people and their admireres closer than ever...

Ledipasvir and Sofosbuvir for 8 or 12 Weeks for Chronic HCV without Cirrhosis

Background High rates of sustained virologic response were observed among patients with hepatitis C virus (HCV) infection who received 12 weeks of treatment with the nucleotide polymerase inhibitor sofosbuvir combined with the NS5A inhibitor ledipasvir....

An Answer to the Question: What Is Enlightenment?

Immanuel Kant's 1784 essay is by far the most famous of the responses to Zollner's request for an answer to the question "What is enlightenment?" Dated 30 September 1784, it was written, as Kant explained in afootnote at the close of the essay, without...

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

BackgroundNintedanib (formerly known as BIBF 1120) is an intracellular inhibitor that targets multiple tyrosine kinases. A phase 2 trial suggested that treatment with 150 mg of nintedanib twice daily reduced lung-function decline and acute exacerbations...

Do Firms Want to Borrow More? Testing Credit Constraints Using a Directed Lending Program

This article uses variation in access to a targeted lending program to estimate whether firms are credit constrained. While both constrained and unconstrained firms may be willing to absorb all the directed credit that they can get (because it may be...

Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

Although stroke is the second leading cause of death worldwide, no comprehensive and comparable assessment of incidence, prevalence, mortality, disability, and epidemiological trends has been estimated for most regions. We used data from the Global Burden...

Goal-Directed Resuscitation for Patients with Early Septic Shock

Sandra L. Peake, Anthony Delaney, Michael Bailey, Rinaldo Bellomo, Peter A. Cameron, James Cooper, Alisa M. Higgins, Anna Holdgate, Belinda D. Howe, Steven A.R. Webb, Patricia Williams, The Australasian Resuscitation in Sepsis Evaluation (ARISE) Investigators...

Erratum to: Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition

Experimental evidence suggests that the maintenance of an item in working memory is achieved through persistent activity in selective neural assemblies of the cortex. To understand the mechanisms underlying this phenomenon, it is essential to investigate...

Recent progress of seismic observation networks in Japan —Hi-net, F-net, K-NET and KiK-net—

After the disastrous 1995 Kobe earthquake, a new national project has started to drastically improve seismic observation system in Japan. A large number of strong-motion, high-sensitivity, and broadband seismographs were installed to construct dense and...

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

BackgroundAlzheimer's disease is characterized by amyloid-beta plaques, neurofibrillary tangles, gliosis, and neuronal loss. Solanezumab, a humanized monoclonal antibody, preferentially binds soluble forms of amyloid and in preclinical studies promoted...

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

Background Bapineuzumab, a humanized anti–amyloid-beta monoclonal antibody, is in clinical development for the treatment of Alzheimer’s disease. Methods We conducted two double-blind, randomized, placebo-controlled, phase 3 trials involving patients...

Some Properties of Symmetric Stable Distributions

This paper takes a few steps toward alleviating problems of data analysis that arise from the fact that elementary expressions for density and cumulative distribution functions (c.d.f.'s) for most stable distributions are unknown. In section 2 results...

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases

.RNA-guided endonucleases (RGENs), derived from the prokaryotic adaptive immune system known as CRISPR/Cas, enable targeted genome engineering in cells and organisms. RGENs are ribonucleoproteins that consist of guide RNA and Cas9, a protein component...

Data Structures and Algorithms in Java

The design and analysis of efficient data structures has long been recognized as a key component of the Computer Science curriculum. Goodrich, Tomassia and Goldwasser's approach to this classic topic is based on the object-oriented paradigm as the framework...

Java in a Nutshell

The sixth edition of Java in a Nutshell helps experienced Java programmers get the most out of Java 7 and 8, but its also a learning path for new developers. With examples rewritten to take full advantage of modern Java APIs and development best practices,...

Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 3-Year Outcomes

The mean (±SD) age of the patients at baseline was 48±8 years, 68% were women, the mean baseline glycated hemoglobin level was 9.3±1.5%, and the mean baseline body-mass index (the weight in kilograms divided by the square of the height in meters) was...

The Heat Balance of the Earth's Surface

The article discusses the present state of knowledge of the basic components of the heat balance of the earth's surface (radiation balance, loss of heat to evaporation, turbulent heat exchange) and the distribution of these components in time and space....

A comprehensive survey: artificial bee colony (ABC) algorithm and applications

Swarm intelligence (SI) is briefly defined as the collective behaviour of decentralized and self-organized swarms. The well known examples for these swarms are bird flocks, fish schools and the colony of social insects such as termites, ants and bees....

Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial

The anti-programmed-death-receptor-1 (PD-1) antibody pembrolizumab has shown potent antitumour activity at different doses and schedules in patients with melanoma. We compared the efficacy and safety of pembrolizumab at doses of 2 mg/kg and 10 mg/kg every...

Health care system

A measurement device (11) measures vital data, encrypts the vital data using an encryption key to generate encrypted vital data, and generates, from a decryption key of the vital data, two pairs of a first share FSD and a second share SSD which enable...

Enzalutamide in Metastatic Prostate Cancer before Chemotherapy

The study was stopped after a planned interim analysis, conducted when 540 deaths had been reported, showed a benefit of the active treatment. The rate of radiographic progression-free survival at 12 months was 65% among patients treated with enzalutamide,...

The present and future role of microfluidics in biomedical research

Eric K. Sackmann, Anna L. Fulton, David J. Beebe

3.5 - Mantle Samples Included in Volcanic Rocks: Xenoliths and Diamonds

Fragments of the Earth’s mantle are frequently transported to the surface via volcanic rocks that are dominantly alkaline in nature. These fragments range up to sizes in excess of 1 m across. The term “mantle xenoliths” or “mantle nodules”...

Hypovitaminosis D myopathy without biochemical signs of osteomalacic bone involvement.

Henning Glerup, Mikkelsen K, Poulsen L, E. Hass, Silke Overbeck, Andersen H, Charles P, Eriksen Ef

Real-Time Implementation of Fault-Tolerant Control Systems With Performance Optimization

In this paper, two online schemes for an integrated design of fault-tolerant control (FTC) systems with application to Tennessee Eastman (TE) benchmark are proposed. Based on the data-driven design of the proposed fault-tolerant architecture whose core...

Multivariate Analysis of Risk Factors for Postoperative Complications in Benign Goiter Surgery: Prospective Multicenter Study in Germany

Oliver Thomusch, Andreas Machens, Carsten Sekulla, Jörg Ukkat, Ingo Gastinger, Henning Dralle

Quantum cascade lasers: a versatile source for precise measurements in the mid/far-infrared range

We provide an overview of recent developments of quantum cascade lasers (QCLs), from the mid-infrared (mid-IR) to the far-IR (THz) range, with a special focus on their metrological-grade applications in a number of fields. A special emphasis on the physics...

Bone graft substitutes

The current gold standard of bone grafts is the autograft since it possesses all the characteristics necessary for new bone growth, namely osteoconductivity, osteogenicity and osteoinductivity. However, the autograft has its limitations, including donor-site...

A non-parametric analysis of recognition experiments'

A non-parametric method for evaluating the results of recognition memory experiments and psychophysical detection experiments is presented. The method is based upon an ordinal analysis of recognition performance, which transforms the results of recognition...

Collaborative learning techniques : a handbook for college faculty

Elizabeth F. Barkley, Claire Howell Major, K. Patricia Cross

Sequence to Sequence Learning with Neural Networks

Deep Neural Networks (DNNs) are powerful models that have achieved excellent performance on difficult learning tasks. Although DNNs work well whenever large labeled training sets are available, they cannot be used to map sequences to sequences. In this...

A guide to genome engineering with programmable nucleases

Programmable nucleases — including zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and RNA-guided engineered nucleases (RGENs) derived from the bacterial clustered regularly interspaced short palindromic repeat...

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A Task Force, supported by the European Respiratory Society and American Thoracic Society, reviewed the definition and provided recommendations and guidelines on the...

A simple, positive semi-definite, heteroscedasticity and autocorrelation consistent covariance matrix

This paper describes a simple method of calculating a heteroskedasticity and autocorrelation consistent covariance matrix that is positive semi-definite by construction. It also establishes consistency of the estimated covariance matrix under fairly general...

Data mining with big data

Big Data concern large-volume, complex, growing data sets with multiple, autonomous sources. With the fast development of networking, data storage, and the data collection capacity, Big Data are now rapidly expanding in all science and engineering domains,...

National survey of doses from CT in the UK: 2003

A review of patient doses from CT examinations in the UK for 2003 has been conducted on the basis of data received from over a quarter of all UK scanners, of which 37% had multislice capability. Questionnaires were employed to collect scan details both...

A theory of organizational knowledge creation

This paper proposes a theory of organizational knowledge creation, which is defined as the process that organizationally amplifies the knowledge created by individuals and crystallizes it as part of the knowledge system of an organization. The process...

Colonoscopic diagnosis and management of nonpolypoid early colorectal cancer

Shin-Ei Kudo, Hiroshi Kashida, Tomoyuki Tamura, Etsuko Kogure, Hiro-o Yamano, Andrew R. Hart

Glove: Global Vectors for Word Representation

Recent methods for learning vector space representations of words have succeeded in capturing fine-grained semantic and syntactic regularities using vector arithmetic, but the origin of these regularities has remained opaque. We analyze and make explicit...

The Endogeneity of Legal Regulation: Grievance Procedures as Rational Myth

Most accounts of organizations and law treat law as largely exogenous and emphasize organizations' responses to law. This study proposes a model of endogeneity among organizations, the professions, and legal institutions. It suggests that organizations...

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

Samuel H. Sternberg, Sy Redding, Martin Jinek, Eric C. Greene, Jennifer A. Doudna

The Cognitive neuropsychology of language

Max Coltheart, Giuseppe Sartori, Remo Job

Chemistry for environmental engineering and science

Clair N. Sawyer, Perry L. McCarty, Gene F. Parkin

Merton, Robert K.

Rebecca D. Petersen

Mortality Related to Severe Sepsis and Septic Shock Among Critically Ill Patients in Australia and New Zealand, 2000-2012

RESULTS Absolute mortality in severe sepsis decreased from 35.0% (95% CI, 33.2%-36.8%; 949/2708) to 18.4% (95% CI, 17.8%-19.0%; 2300/12 512; P < .001), representing an overall decrease of 16.7% (95% CI, 14.8%-18.6%),...

Dosimetry of two extraoral direct digital imaging devices: NewTom cone beam CT and Orthophos Plus DS panoramic unit

Objectives:This study provides effective dose measurements for two extraoral direct digital imaging devices, the NewTom 9000™ cone beam CT (CBCT) unit and the Orthophos Plus DS panoramic unit. Methods:Thermoluminescent dosemeters were placed at 20 sites...

BEAST 2: a software platform for Bayesian evolutionary analysis.

Remco Bouckaert, Joseph Heled, Denise Kühnert, Timothy G. Vaughan, Chieh-Hsi Wu, Dong Xie, Marc A. Suchard, Andrew Rambaut, Alexei J. Drummond

Fluorescent sensors for measuring metal ions in living systems.

Kyle P. Carter, Alexandra M Young, Amy E. Palmer

Social Justice Research

Kjell Törnblom, Ali Kazemi

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

Peter E. Czabotar, Guillaume Lessene, Andreas Strasser, Jerry M. Adams

Total Knee Replacement in Young, Active Patients: Long-Term Follow-up and Functional Outcome

: Concern exists regarding the long-term durability and effectiveness of total knee arthroplasty in young patients. We reviewed our experience with total knee arthroplasty in patients fifty-five years old and younger with severe osteoarthritis to determine...

Genetics of rheumatoid arthritis contributes to biology and drug discovery

A major challenge in human genetics is to devise a systematic strategy to integrate diseaseassociated variants with diverse genomic and biological datasets to provide insight into disease pathogenesis and guide drug discovery for complex traits such as...

Worldwide Epidemiology of Atrial Fibrillation A Global Burden of Disease 2010 Study

Background —The global burden of atrial fibrillation (AF) is unknown. Methods and Results —We systematically reviewed population-based studies of AF published 1980-2010, from the 21 Global Burden of Disease (GBD) regions to estimate global/regional...

Entropy in the sense of Boltzmann and Poincaré

The H-theorem is proved for generalized equations of chemical kinetics, and important physical examples of such generalizations are considered: a?discrete model of the quantum kinetic equations (the Uehling-Uhlenbeck equations) and a?quantum Markov process...

A chromosome-based draft sequence of the hexaploid bread wheat (Triticum aestivum) genome

An ordered draft sequence of the 17-gigabase hexaploid bread wheat (Triticum aestivum) genome has been produced by sequencing isolated chromosome arms. We have annotated 124,201 gene loci distributed nearly evenly across the homeologous chromosomes and...

Systematic review of randomized trials of the effect of exercise on bone mass in pre- and postmenopausal women.

Studies of the effect of exercise programs on bone mass appear inconsistent. Our objective was to sys- tematically review and meta-analyze randomized trials of the effect of exercise on bone mass in pre- and postmeno- pausal women. A computerized MEDLINE...

CpG DNA as a vaccine adjuvant

Synthetic oligodeoxynucleotides containing unmethylated CpG motifs act as immune adjuvants, accelerating and boosting antigen-specific antibody responses by up to 500-fold. CpG motifs promote the production of T-helper 1 and pro-inflammatory cytokines...

Additive Enhanced Crystallization of Solution‐Processed Perovskite for Highly Efficient Planar‐Heterojunction Solar Cells

Po-Wei Liang, Chien-Yi Liao, Chu‐Chen Chueh, Fan Zuo, Spencer T. Williams, Xukai Xin, Jiang-Jen Lin, Alex K.-Y. Jen

OARSI guidelines for the non-surgical management of knee osteoarthritis.

To develop concise, up-to-date, patient-focused, evidence-based, expert consensus guidelines for the management of knee osteoarthritis (OA), intended to inform patients, physicians, and allied healthcare professionals worldwide.

Perfusion CT: a worthwhile enhancement?

Kenneth A. Miles, Matthew Griffiths

Handbook of Virtual Environments: Design, Implementation, and Applications

A Complete Toolbox of Theories and Techniques The second edition of a bestseller, Handbook of Virtual Environments: Design, Implementation, and Applications presents systematic and extensive coverage of the primary areas of research and development within...

Energy balance of optical breakdown in water at nanosecond to femtosecond time scales

During optical breakdown, the energy delivered to the sample is either transmitted, reflected, scattered, or ab- sorbed. Pathways for the division of the absorbed energy are the evaporation of the focal volume, the plasma radiation, and the mechanical...

First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer

Progression-free survival was significantly longer with crizotinib than with chemotherapy (median, 10.9 months vs. 7.0 months; hazard ratio for progression or death with crizotinib, 0.45; 95% confidence interval [CI],...

Procedural sedation and analgesia in children

This video shows the technique of procedural sedation and analgesia in children, reviewing indications, patient assessment, the use of sedative and analgesic drugs, potential adverse events, recovery, and discharge from the hospital.

Adolescent development and the onset of drinking. A longitudinal study.

Junior and senior high-school students were studied over a 4-year period. The likelihood of drinking was directly related to the degree of transition- or problem-proneness, and a developmental relationship between onset of drinking and other socipsychological...

A Review on Basic Data-Driven Approaches for Industrial Process Monitoring

Recently, to ensure the reliability and safety of modern large-scale industrial processes, data-driven methods have been receiving considerably increasing attention, particularly for the purpose of process monitoring. However, great challenges are also...

Hydrothermal carbonization of biomass residuals: a comparative review of the chemistry, processes and applications of wet and dry pyrolysis

The carbonization of biomass residuals to char has strong potential to become an environmentally sound conversion process for the production of a wide variety of products. In addition to its traditional use for the production of charcoal and other energy...

Sixth INTERMACS annual report: A 10,000-patient database

James K. Kirklin, David C. Naftel, Francis D. Pagani, Robert L. Kormos, Elizabeth D. Blume, Marissa A. Miller, J.T. Baldwin, James B. Young

Molecular Design toward Highly Efficient Photovoltaic Polymers Based on Two-Dimensional Conjugated Benzodithiophene

ConspectusAs researchers continue to develop new organic materials for solar cells, benzo[1,2-b:4,5-b']dithiophene (BDT)-based polymers have come to the fore. To improve the photovoltaic properties of BDT-based polymers, researchers have developed and...

Vaccines for fish in aquaculture

Vaccination plays an important role in large-scale commercial fish farming and has been a key reason for the success of salmon cultivation. In addition to salmon and trout, commercial vaccines are available for channel catfish, European seabass and seabream,...

Proximal Algorithms

This monograph is about a class of optimization algorithms called proximal algorithms. Much like Newton's method is a standard tool for solving unconstrained smooth optimization problems of modest size, proximal algorithms can be viewed as an analogous...

Does Gamification Work? -- A Literature Review of Empirical Studies on Gamification

This paper reviews peer-reviewed empirical studies on gamification. We create a framework for examining the effects of gamification by drawing from the definitions of gamification and the discussion on motivational affordances. The literature review covers...

Play and Intrinsic Rewards

Play and Intrinsic Rewards

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