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Publications in 2014

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Biological insights from 108 schizophrenia-associated genetic loci

Summary Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wide association studies. Here, we report a multi-stage schizophrenia...

Discovery and saturation analysis of cancer genes across 21 tumour types

Although a few cancer genes are mutated in a high proportion of tumours of a given type (.20%), most are mutated at intermediate frequencies (2–20%). To explore the feasibility of creating a comprehensive catalogue of cancer genes, we analysed somatic...

Linear mixed models : a practical guide using statistical software

Brady T. West, Kathleen Welch, Andrzej T. Galecki, Brenda W. Gillespie

Soil fertility and fertilizers : an introduction to nutrient management

Soil fertility and fertilizers : an introduction to nutrient management

Changes in the global value of ecosystem services

In 1997, the global value of ecosystem services was estimated to average $33 trillion/yr in 1995 $US ($46 trillion/yr in 2007 $US). In this paper, we provide an updated estimate based on updated unit ecosystem service values and land use change estimates...

The Second Machine Age: Work, Progress, and Prosperity in a Time of Brilliant Technologies

A New York Times Bestseller A revolution is under way. In recent years, Googles autonomous cars have logged thousands of miles on American highways and IBMs Watson trounced the best human Jeopardy! players. Digital technologieswith hardware, software,...

Massive MIMO for next generation wireless systems

Multi-user MIMO offers big advantages over conventional point-to-point MIMO: it works with cheap single-antenna terminals, a rich scattering environment is not required, and resource allocation is simplified because every active terminal utilizes all...

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

Methods We randomly assigned eligible patients to either intraarterial treatment plus usual care or usual care alone. Eligible patients had a proximal arterial occlusion in the anterior cerebral circulation that was confirmed on vessel imaging and that...

Modeling the Spatial Dynamics of Regional Land Use: The CLUE-S Model

Peter H. Verburg, Welmoed Soepboer, A. Veldkamp, Ramil Limpiada, Victoria O. Espaldon, Sharifah Sa Mastura

[2014 ESC/EACTS Guidelines on myocardial revascularization].

Stephan Windecker, Philippe Kolh, Fernando Alfonso, Jean-Philippe Collet, Jochen Cremer, Volkmar Falk, Gerasimos Filippatos, Christian W. Hamm, Stuart J. Head, Peter Jüni, A. Pieter Kappetein, Adnan Kastrati, Juhani Knuuti, Ulf Landmesser, Günther Laufer, Franz-Josef Neumann, Dimitrios J. Richter, Patrick Schauerte, Miguel Sousa Uva, Giulio G. Stefanini, David P. Taggart, Lucia Torracca, Marco Valgimigli, William Wijns, Adam Witkowski

Racial Formation in the United States

Michael Omi, Howard Winant

Diet rapidly and reproducibly alters the human gut microbiome

Long-term diet influences the structure and activity of the trillions of microorganisms residing in the human gut 1–5 , but it remains unclear how rapidly and reproducibly the human gut microbiome responds to short-term macronutrient change. Here, we...

Ledipasvir and Sofosbuvir for Untreated HCV Genotype 1 Infection

RESULTS Of the 865 patients who underwent randomization and were treated, 16% had cirrhosis, 12% were black, and 67% had HCV genotype 1a infection. The rates of sustained virologic response were 99% (95% confidence interval [CI], 96 to 100) in the group...

Discovering Knowledge in Data: An Introduction to Data Mining

The second edition of a highly praised, successful reference on data mining, with thorough coverage of big data applications, predictive analytics, and statistical analysis.Includes new chapters on Multivariate Statistics, Preparing to Model the Data,...

The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009)

Toshio Ogihara, Kenjiro Kikuchi, Hiroaki Matsuoka, Toshiro Fujita, Jitsuo Higaki, Masatsugu Horiuchi, Yutaka Imai, Tsutomu Imaizumi, Sadayoshi Ito, Hiroshi Iwao, Kazuomi Kario, Yuhei Kawano, Shokei Kim-Mitsuyama, Genjiro Kimura, Hiroaki Matsubara, Mitsuhide Naruse, Ikuo Saito, Kazuyuki Shimada, Kazuaki Shimamoto, Hiromichi Suzuki, Shuichi Takishita, Norio Tanahashi, Takuya Tsuchihashi, Shinichiro Ueda, Hirotsugu Ueshima, Satoshi Umemura, Toshihiko Ishimitsu, Hiromi Rakugi

Household Food Security in the United States in 2013

An estimated 85.7 percent of American households were food secure throughout the entire year in 2013, meaning that they had access at all times to enough food for an active, healthy life for all household members. The remaining households (14.3 percent)...

Morphological Control for High Performance, Solution‐Processed Planar Heterojunction Perovskite Solar Cells

Organometal trihalide perovskite based solar cells have exhibited the highest efficiencies to-date when incorporated into mesostructured composites. However, thin solid films of a perovskite absorber should be capable of operating at the highest efficiency...

Evolutionary computation: a unified approach

The field of Evolutionary Computation has experienced tremendous growth over the past 25 years, resulting in a wide variety of evolutionary algorithms and applications. The result poses an interesting dilemma for many practitioners in the sense that,...

Updated high‐resolution grids of monthly climatic observations – the CRU TS3.10 Dataset

This paper describes the construction of an updated gridded climate dataset (referred to as CRU TS3.10) from monthly observations at meteorological stations across the world's land areas. Station anomalies (from 1961 to 1990 means) were interpolated into...

The Stanford CoreNLP Natural Language Processing Toolkit

We describe the design and use of the Stanford CoreNLP toolkit, an extensible pipeline that provides core natural language analysis. This toolkit is quite widely used, both in the research NLP community and also among commercial and government users of...

Global estimates of diabetes prevalence for 2013 and projections for 2035

Diabetes is a serious and increasing global health burden and estimates of prevalence are essential for appropriate allocation of resources and monitoring of trends.

Transcatheter aortic-valve replacement with a self-expanding prosthesis.

Background We compared transcatheter aortic-valve replacement (TAVR), using a self-expanding transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in patients with severe aortic stenosis and an increased risk of death during...

Circular Dichroism and Linear Dichroism

Chalmers Publication Library (CPL). Forskningspublikationer fran Chalmers Tekniska Hogskola.

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

Jiang Wang, Maria Sanchez‐Rosello, José Luis Aceña, Carlos del Pozo, Alexander E. Sorochinsky, Santos Fustero, Vadim A. Soloshonok, Hong Liu

Regulation of microRNA biogenesis

MicroRNAs (mi RNAs) are small non-coding RNAs that function as guide molecules in RNA silencing. Targeting most protein-coding transcripts, mi RNAs are involved in nearly all developmental and pathological processes in animals. The biogenesis of mi RNAs...

DeepFace: Closing the Gap to Human-Level Performance in Face Verification

In modern face recognition, the conventional pipeline consists of four stages: detect => align => represent => classify. We revisit both the alignment step and the representation step by employing explicit 3D face modeling in order to apply a piecewise...

Emergence of Zaire Ebola Virus Disease in Guinea

In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the...

Gold nanoparticles: a new X-ray contrast agent

There have been few fundamental improvements in clinical X-ray contrast agents in more than 25 years, and the chemical platform of tri-iodobenzene has not changed. Current agents impose serious limitations on medical imaging: short imaging times, the...

Daclatasvir plus Sofosbuvir for Previously Treated or Untreated Chronic HCV Infection

Background All-oral combination therapy is desirable for patients with chronic hepatitis C virus (HCV) infection. We evaluated daclatasvir (an HCV NS5A replication complex inhibitor) plus sofosbuvir (a nucleotide analogue HCV NS5B polymerase inhibitor)...

Cancer risks from diagnostic radiology

In recent years, there has been a rapid increase in the number of CT scans performed, both in the US and the UK, which has fuelled concern about the long-term consequences of these exposures, particularly in terms of cancer induction. Statistics from...

The new frontier of genome engineering with CRISPR-Cas9

The advent of facile genome engineering using the bacterial RNA-guided CRISPR-Cas9 system in animals and plants is transforming biology. We review the history of CRISPR (clustered regularly interspaced palindromic repeat) biology from its initial discovery...

Flow study in relativistic nuclear collisions by Fourier expansion of azimuthal particle distributions

: We propose a new method to study transverse flow effects in relativistic nuclear collisions by Fourier analysis of the azimuthal distribution on an event-by-event basis in relatively narrow rapidity windows. The distributions of Fourier coefficients...

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

Four new oral anticoagulants compare favourably with warfarin for stroke prevention in patients with atrial fibrillation; however, the balance between efficacy and safety in subgroups needs better definition. We aimed to assess the relative benefit of...

EAU Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent—Update 2013

The most recent summary of the European Association of Urology (EAU) guidelines on prostate cancer (PCa) was published in 2011.

Dosimetry of 3 CBCT devices for oral and maxillofacial radiology: CB Mercuray, NewTom 3G and i-CAT

Objectives: Cone beam computed tomography (CBCT), which provides a lower dose, lower cost alternative to conventional CT, is being used with increasing frequency in the practice of oral and maxillofacial radiology. This study provides comparative measurements...

Recent advances in semiconductors for photocatalytic and photoelectrochemical water splitting

Photocatalytic and photoelectrochemical water splitting under irradiation by sunlight has received much attention for production of renewable hydrogen from water on a large scale. Many challenges still remain in improving energy conversion efficiency,...

Planck 2013 results - I. Overview of products and scientific results

The Planck Collaboration acknowledge the support of: ESA; CNES and CNRS/INSU-IN2P3-INP (France); ASI, CNR, and INAF (Italy); NASA and DoE (USA); STFC and UKSA (UK); CSIC, MICINN and JA (Spain); Tekes, AoF and CSC (Finland); DLR and MPG (Germany); CSA...

The neural basis of oral and facial function

This article provides an outline of the neural mechanisms that are involved in the somatosensory and motor functions of the face and mouth and, in a more limited sense, of the pharynx and larynx. The article focuses on the neural basis of orofacial touch,...

Satellite remote sensing of wetlands

Stacy L. Ozesmi, Marvin E. Bauer

ImageNet Large Scale Visual Recognition Challenge

: The ImageNet Large Scale Visual Recognition Challenge is a benchmark in object category classification and detection on hundreds of object categories and millions of images. The challenge has been run annually from 2010 to present, attracting participation...

2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society

Michael D. Jensen, Donna H. Ryan, Caroline M. Apovian, Jamy D. Ard, Anthony G. Comuzzie, Karen A. Donato, Frank B. Hu, Van S. Hubbard, John M. Jakicic, Catherine M. Loria, Barbara E. Millen, Cathy Nonas, F. Xavier Pi-Sunyer, June Stevens, Victor J. Stevens, Thomas A. Wadden, Bruce M. Wolfe, Susan Z. Yanovski

The Absence of the African-American Owned Business: An Analysis of the Dynamics of Self-Employment

Estimates from the Panel Study of Income Dynamics indicate that African‐American men are one‐third as likely to be self‐employed as white men. The large discrepancy is due to a black transition rate into self‐employment that is approximately one‐half...

The emergence of perovskite solar cells

Martin A. Green, Anita Ho-Baillie, Henry J. Snaith

Cosmochemical Estimates of Mantle Composition

The composition of the primitive mantle derived here shows that Earth was assembled from material that shows many of the same chemical fractionation processes as chondritic meteorites. These processes occurred at the initial stage of the solar system...

What Will 5G Be

What will 5G be? What it will not be is an incrementaladvance on 4G. The previous four generations ofcellular technology have each been a major paradigm shiftthat has broken backwards compatibility. And indeed, 5G willneed to be a paradigm shift that...

Development of a compact computed tomographic apparatus for dental use.

OBJECTIVE To describe a compact computed tomographic apparatus (Ortho-CT) for use in dental practice. METHODS Ortho-CT is a cone-beam-type of CT apparatus consisting of a multifunctional maxillofacial imaging machine (Scanora, Soredex, Helsinki, Finland)...

Some Estimators for a Linear Model With Random Coefficients

The linear model given by is considered. The βk represent average responses of yt the dependent variable to unit changes in the independent variables, ztk. The vtk are independently distributed random errors. A number of consistent estimators of the...

A Randomized Trial of Protocol-Based Care for Early Septic Shock

In 31 emergency departments in the United States, we randomly assigned patients with septic shock to one of three groups for 6 hours of resuscitation: protocol-based EGDT; protocol-based standard therapy that did not require the placement of a central...

Finite Elements and Fast Iterative Solvers: With Applications in Incompressible Fluid Dynamics

The intended readership includes graduate students and researchers in engineering, numerical analysis, applied mathematics and interdisciplinary scientific computing. The publisher describes the book as follows:* An excellent introduction to finite elements,...

Workflows for e-Science: Scientific Workflows for Grids

This is a timely book presenting an overview of the current state-of-the-art within established projects, presenting many different aspects of workflow from users to tool builders. It provides an overview of active research, from a number of different...

Device Characteristics of CZTSSe Thin‐Film Solar Cells with 12.6% Efficiency

Wei Wang, Mark T. Winkler, Oki Gunawan, Tayfun Gokmen, Teodor K. Todorov, Yu Zhu, David B. Mitzi

CNN Features Off-the-Shelf: An Astounding Baseline for Recognition

Recent results indicate that the generic descriptors extracted from the convolutional neural networks are very powerful. This paper adds to the mounting evidence that this is indeed the case. We report on a series of experiments conducted for different...

Popper, Karl R

Anne Fagot-Largeault

epic3: National Evidence-Based Guidelines for Preventing Healthcare-Associated Infections in NHS Hospitals in England

National evidence-based guidelines for preventing healthcare-associated infections (HCAI) in National Health Service (NHS) hospitals in England were originally commissioned by the Department of Health and developed during 1998–2000 by a nurse-led multi-professional...

Non-rigid image registration: theory and practice

Image registration is an important enabling technology in medical image analysis. The current emphasis is on development and validation of application-specific non-rigid techniques, but there is already a plethora of techniques and terminology in use....

The New Statistics Why and How

We need to make substantial changes to how we conduct research. First, in response to heightened concern that our published research literature is incomplete and untrustworthy, we need new requirements to ensure research integrity. These include prespecification...

Colorectal cancer statistics, 2014

Rebecca Siegel, Carol DeSantis, Ahmedin Jemal

Coloured Petri Nets: Modelling and Validation of Concurrent Systems

Coloured Petri Nets (CPN) is a graphical language for modelling and validating concurrent and distributed systems, and other systems in which concurrency plays a major role. The development of such systems is particularly challenging because of inherent...

Clinician’s Guide to Prevention and Treatment of Osteoporosis

The Clinician’s Guide to Prevention and Treatment of Osteoporosis was developed by an expert committee of the National Osteoporosis Foundation (NOF) in collaboration with a multispecialty council of medical experts in the field of bone health convened...

Exercise for intermittent claudication

Patient AccessPatients and/or caregivers may access this content for use in relation to their own personal healthcare or that of a family member only. Terms and conditions will apply.

Comprehensive molecular characterization of gastric adenocarcinoma

Adam J. Bass, Vesteinn Thorsson, Ilya Shmulevich, Sheila M. Reynolds, Michael Miller, Brady Bernard, Toshinori Hinoue, Peter W. Laird, Christina Curtis, Hui Shen, Daniel J. Weisenberger, Nikolaus Schultz, Ronglai Shen, Nils Weinhold, David P. Kelsen, Reanne Bowlby, Andy Chu, Katayoon Kasaian, Andrew J. Mungall, A. Gordon Robertson, Payal Sipahimalani, Andrew D. Cherniack, Gad Getz, Yingchun Liu, Michael S. Noble, Chandra Pedamallu, Carrie Sougnez, Amaro Taylor-Weiner, Rehan Akbani, Ju-Seog Lee, Wenbin Liu, Gordon Mills, Yang D, Wei Zhang, Angeliki Pantazi, Michael Parfenov, Margaret L. Gulley, M. Blanca Piazuelo, Barbara G. Schneider, Jihun Kim, Alex Boussioutas, Margi Sheth, John A. Demchok, Charles S. Rabkin, Joseph Willis, Sam Ng, Katherine S. Garman, David G. Beer, Arjun Pennathur, Benjamin J. Raphael

2013 AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Robert H. Eckel, John M. Jakicic, Jamy D. Ard, Janet M. de Jesus, Nancy Houston Miller, Van S. Hubbard, I-Min Lee, Alice H. Lichtenstein, Catherine M. Loria, Barbara E. Millen, Cathy A. Nonas, Frank M. Sacks, Sidney C. Smith, Laura P. Svetkey, Thomas A. Wadden, Susan Z. Yanovski

Product-Focused Software Process Improvement

Frank Bomarius, Seija Komi-Sirviö

Climate Change 2013: The Physical Science Basis. Contribution of Working Group I to the Fifth Assessment Report of IPCC the Intergovernmental Panel on Climate Change

T. F. Stocker, D. Qin, G.-K. Plattner, M. M. B. Tignor, S. K. Allen, J. Boschung, A. Nauels, Y. Xia, V. Bex, P. M. Midgley

The neurobiology of suicide

The stress–diathesis model posits that suicide is the result of an interaction between state-dependent (environmental) stressors and a trait-like diathesis or susceptibility to suicidal behaviour, independent of psychiatric disorders. Findings from...

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY (http://www.guidetopharmacology.org) is a new open access resource providing pharmacological, chemical, genetic, functional and...

Nation branding : concepts, issues, practice

Comprehensive text that demonstrates why nations are embracing the principles of brand management. It clearly explains how the concepts and techniques of branding can be adapted to the context of nations- as opposed to the more usual context of products,...

Correlation Between Dopamine D2 Receptors in the Ventral Striatum and Central Processing of Alcohol Cues and Craving

Objective: Alcohol and other drugs of abuse stimulate dopamine release in the ventral striatum, which includes the nucleus accumbens, a core region of the brain reward system, and reinforce substance intake. Chronic alcohol intake is associated with down-regulation...

Large Eddy Simulation and the variational multiscale method

A Large Eddy Simulation (LES) formulation is developed from the variational multiscale method. Model- ing is confined to the effect of a small-scale Reynolds stress, in contrast with classical LES in which the entire subgrid- scale stress is modeled....

Ribosomal Database Project: data and tools for high throughput rRNA analysis

Ribosomal Database Project (RDP; http://rdp.cme. msu.edu/) provides the research community with aligned and annotated rRNA gene sequence data, along with tools to allow researchers to analyze their own rRNA gene sequences in the RDP framework. RDP data...

State, power, socialism

Nicos Poulantzas, Stuart Hall, Patrick Camiller

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens malaria control and elimination activities worldwide. To monitor the spread of artemisinin resistance, a molecular marker is urgently needed. Here, using whole-genome...

Deep Learning in Neural Networks: An Overview

a b s t r a c t In recent years, deep artificial neural networks (including recurrent ones) have won numerous contests in pattern recognition and machine learning. This historical survey compactly summarizes relevant work, much of it from the previous...

Surface‐subsurface model intercomparison: A first set of benchmark results to diagnose integrated hydrology and feedbacks

Mario Putti, Steven B. Meyerhoff, Jens-Olaf Delfs, Ian M. Ferguson, Valeriy Y. Ivanov, Jongho Kim, Olaf Kolditz, Stefan J. Kollet, Mukesh Kumar, Sonya Lopez, Jie Niu, Claudio Paniconi, Young Bae Park, Mantha S. Phanikumar, Chaopeng Shen, Mauro Sulis

De novo mutations in schizophrenia implicate synaptic networks

Inherited alleles account for most of the genetic risk for schizophrenia. However, new (de novo) mutations, in the form of large chromosomal copy number changes, occur in a small fraction of cases and disproportionally disrupt genes encoding postsynaptic...

Multimodal teaching and learning : the rhetorics of the science classroom

Gunther Kress, Carey Jewitt, Jon Ogborn, Charalampos Tsatsarelis

Reactivity of solids

A review of studies of reactivities of solids is presented, concentrating on localization and autolocalization phenomena. Some examples of feed-back and structure of the reaction zone are given.

4.21 - One View of the Geochemistry of Subduction-Related Magmatic Arcs, with an Emphasis on Primitive Andesite and Lower Crust

This chapter has four main aims. Provide a comprehensive picture of the composition of volcanic rocks from subduction-related magmatic arcs. Review evidence in favor of the existence of andesitic, as well as basaltic primary magmas in arcs. Present new...

On the Slope-Aspect Correction of Multispectral Scanner Data

SUMMARYThe effects of topography on the radiometric properties of multispectral scanner (MSS) data are examined in the context of the remote sensing of forests in mountainous regions. The two test areas considered for this study are located in the coastal...

Deciphering key features in protein structures with the new ENDscript server

ENDscript 2 is a friendly Web server for extracting and rendering a comprehensive analysis of primary to quaternary protein structure information in an automated way. This major upgrade has been fully reengineered to enhance speed, accuracy and usability...

Low-Temperature Solution-Processed Perovskite Solar Cells with High Efficiency and Flexibility

Perovskite compounds have attracted recently great attention in photovoltaic research. The devices are typically fabricated using condensed or mesoporous TiO2 as the electron transport layer and 2,2′7,7′-tetrakis-(N,N-dip-methoxyphenylamine)9,9′-spirobifluorene...

The Aetiology of Primary Osteoarthritis of the Hip

In most reports on osteoarthritis of the hip approximately half the patients have presented in adult life with no relevant antecedent history. In order to assess, in such cases of so-called primary osteoarthritis, the presence of any minor pre-existing...

The customs union issue

Jacob Viner's The Customs Union Issue was originally published in 1950 by the Carnegie Endowment for International Peace. It set the framework for the contemporary debate over the benefits or otherwise of preferential trading agreements such as the European...

The Tenth Data Release Of The Sloan Digital Sky Survey: First Spectroscopic Data From The Sdss-Iii Apache Point Observatory Galactic Evolution Experiment

The Sloan Digital Sky Survey (SDSS) has been in operation since 2000 April. This paper presents the Tenth Public Data Release (DR10) from its current incarnation, SDSS-III. This data release includes the first spectroscopic data from the Apache Point...

Measuring individual tree crown diameter with lidar and assessing its influence on estimating forest volume and biomass

The main objective of this study was to develop reliable processing and analysis techniques to facilitate the use of small-footprint lidar data for estimating tree crown diameter by measuring individual trees identifiable on the three-dimensional lidar...

High intensity focused ultrasound: surgery of the future?

High intensity focused ultrasound: surgery of the future? For 50 years, high intensity focused ultrasound (HIFU) has been a subject of interest for medical research. HIFU causes selective tissue necrosis in a very well defined volume, at a variable distance...

Risk of childhood cancer from fetal irradiation.

The association between the low dose of ionizing radiation received by the fetus in utero from diagnostic radiography, particularly in the last trimester of pregnancy, and the subsequent risk of cancer in childhood provides direct evidence against the...

3D bioprinting of tissues and organs

Sean V. Murphy, Anthony Atala

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

The development of noninvasive methods to detect and monitor tumors continues to be a major challenge in oncology. We used digital polymerase chain reaction–based technologies to evaluate the ability of circulating tumor DNA (ctDNA) to detect tumors...

The M1 and M2 paradigm of macrophage activation: time for reassessment

Macrophages are endowed with a variety of receptors for lineage-determining growth factors, T helper (Th) cell cytokines, and B cell, host, and microbial products. In tissues, macrophages mature and are activated in a dynamic response to combinations...

Computerized transverse axial scanning (tomography): Part 2. Clinical application*

A new and fundamentally different X-ray method is described. The cranium is scanned in successive layers by a narrow beam of X rays, in such a way that the transmission of the X-ray photons across a particular layer can be measured, and by means of a...

Exercise based rehabilitation for heart failure

Background From previous systematic reviews and meta-analyses there is consensus about the positive effect of exercise training on exercise capacity; however, the effects on health-related quality of life, mortality and hospital admissions in heart failure...

Artificial Intelligence and Soft Computing

Leszek Rutkowski, Marcin Korytkowski, Rafal Scherer, Ryszard Tadeusiewicz, Lotfi A. Zadeh, Jacek M. Zurada

The Bounds of Reason: Game Theory and the Unification of the Behavioral Sciences

Game theory is central to understanding human behavior and relevant to all of the behavioral sciences—from biology and economics, to anthropology and political science. However, as The Bounds of Reason demonstrates, game theory alone cannot fully explain...

Prokka: rapid prokaryotic genome annotation

Summary: The multiplex capability and high yield of current day DNAsequencing instruments has made bacterial whole genome sequencing a routine affair. The subsequent de novo assembly of reads into contigs has been well addressed. The final step of annotating...

Perovskite solar cells employing organic charge-transport layers

Olga Malinkiewicz, Aswani Yella, Yong Hui Lee, Guillermo Mínguez Espallargas, Michael Graetzel, Mohammad K. Nazeeruddin, Henk J. Bolink

Large-Scale Video Classification with Convolutional Neural Networks

Convolutional Neural Networks (CNNs) have been established as a powerful class of models for image recognition problems. Encouraged by these results, we provide an extensive empirical evaluation of CNNs on large-scale video classification using a new...

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