CiteWeb

WorldWeb citation database

Publications in 2012

Page 8
Variance Function Estimation

Heteroscedastic regression models are used in fields including economics, engineering, and the biological and physical sciences. Often, the heteroscedasticity is modeled as a function of the covariates or the regression and other structural parameters....

Anomalous Zero-Bias Conductance Peak in a Nb-InSb Nanowire-Nb Hybrid Device.

Semiconductor InSb nanowires are expected to provide an excellent material platform for the study of Majorana fermions in solid state systems. Here, we report on the realization of a Nb–InSb nanowire–Nb hybrid quantum device and the observation of...

A National Estimate of the Economic Costs of Asthma

This cost of illness analysis examines national cost and resource utilization by persons with asthma using a single, comprehensive data source, the 1987 National Medical Expenditure Survey. Direct medical expenditures included payments for ambulatory...

Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease (CE-MARC): a prospective trial.

Summary Background In patients with suspected coronary heart disease, single-photon emission computed tomog raphy (SPECT) is the most widely used test for the assessment of myocardial ischaemia, but its diagnostic accuracy is reported to be variable and...

The long-range interaction landscape of gene promoters

Amartya Sanyal, Bryan R. Lajoie, Gaurav Jain, Job Dekker

Inspiratory Pressure Support Prevents Diaphragmatic Fatigue during Weaning from Mechanical Ventilation

Persistent inability to tolerate discontinuation from mechanical ventilation is frequently encountered in patients recovering from acute respiratory failure. We studied the ability of inspiratory pressure support, a new mode of ventilatory assistance,...

Reduction in Inappropriate Therapy and Mortality through ICD Programming

We randomly assigned 1500 patients with a primary-prevention indication to receive an ICD with one of three programming configurations. The primary objective was to determine whether programmed high-rate therapy (with a 2.5-second delay before the initiation...

Modeling and Analysis of K-Tier Downlink Heterogeneous Cellular Networks

Cellular networks are in a major transition from a carefully planned set of large tower-mounted base-stations (BSs) to an irregular deployment of heterogeneous infrastructure elements that often additionally includes micro, pico, and femtocells, as well...

Accuracy of finite‐difference and finite‐element modeling of the scalar and elastic wave equations

Numerical solutions of the scalar and elastic wave equations have greatly aided geophysicists in both forward modeling and migration of seismic wave fields in complicated geologic media, and they promise to be invaluable in solving the full inverse problem....

Emerging fungal threats to animal, plant and ecosystem health

The past two decades have seen an increasing number of virulent infectious diseases in natural populations and managed landscapes. In both animals and plants, an unprecedented number of fungal and fungal-like diseases have recently caused some of the...

Progress in Chemical-Looping Combustion and Reforming technologies

This work is a comprehensive review of the Chemical-Looping Combustion (CLC) and Chemical-Looping Reforming (CLR) processes reporting the main advances in these technologies up to 2010. These processes are based on the transfer of the oxygen from air...

Eliminating Waste in US Health Care

Donald M. Berwick, Andrew D. Hackbarth

Acute Kidney Injury

SummaryAcute kidney injury (formerly known as acute renal failure) is a syndrome characterised by the rapid loss of the kidney's excretory function and is typically diagnosed by the accumulation of end products of nitrogen metabolism (urea and creatinine)...

Cautionary Note about R 2

The coefficient of determination (R 2) is perhaps the single most extensively used measure of goodness of fit for regression models. It is also widely misused. The primary source of the problem is that except for linear models with an intercept term,...

Early signs of atherosclerosis in obstructive sleep apnea.

Background: Obstructive sleep apnea (OSA) is associated with several cardiovascular diseases. However, the mechanisms are not completely understood. Recent studies have shown that OSA is associated with multiple markers of endothelial damage. We hypothesized...

On the Fit of New Keynesian Models

This article provides new tools for the evaluation of dynamic stochastic general equilibrium (DSGE) models and applies them to a large-scale new Keynesian model. We approximate the DSGE model by a vector autoregression, and then systematically relax the...

An Approximate Analysis of Variance Test for Normality

This article presents a modification of the Shapiro-Wilk W statistic for testing normality which can be used with large samples. Shapiro and Wilk gave coefficients and percentage points for sample sizes up to 50. These coefflcients required obtaining...

Efficient Additive Kernels via Explicit Feature Maps

Large scale nonlinear support vector machines (SVMs) can be approximated by linear ones using a suitable feature map. The linear SVMs are in general much faster to learn and evaluate (test) than the original nonlinear SVMs. This work introduces explicit...

Exercise-Induced Muscle Damage and Adaptation

Exercise-Induced Muscle Damage and Adaptation

A Predictive Approach to Model Selection

This article offers a synthesis of Bayesian and sample-reuse approaches to the problem of high structure model selection geared to prediction. Similar methods are used for low structure models. Nested and nonnested paradigms are discussed and examples...

Hyperdimensional Data Analysis Using Parallel Coordinates

This article presents the basic results of using the parallel coordinate representation as a high-dimensional data analysis tool. Several alternatives are reviewed. The basic algorithm for parallel coordinates is laid out and a discussion of its properties...

Interpolation using surface splines.

Ross Harder, Robert Desmarais

Impacts of climate change on the future of biodiversity

Many studies in recent years have investigated the effects of climate change on the future of biodiversity. In this review, we first examine the different possible effects of climate change that can operate at individual, population, species, community,...

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer.

Debbie Saslow, Diane Solomon, Herschel W. Lawson, Maureen Killackey, Shalini Kulasingam, Joanna M. Cain, Francisco Garcia, Ann T. Moriarty, Alan Waxman, David C. Wilbur, Levi S. Downs, Mark Spitzer, Anna-Barbara Moscicki, Eduardo L. Franco, Mark H. Stoler, Philip E. Castle, Evan R. Myers

Addition of Aflibercept to Fluorouracil, Leucovorin, and Irinotecan Improves Survival in a Phase III Randomized Trial in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen

Purpose Treatment for metastatic colorectal cancer (mCRC) commonly involves a fluoropyrimidine-based chemotherapy regimen such as infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) or fluorouracil, leucovorin, and oxaliplatin, often combined...

Comfort your online customer: quality, trust and loyalty on the internet

In e‐commerce, loyal customers are considered extremely valuable. Loyalty is generally attributed to satisfaction with the quality of service. Since online transactions involve many uncertainties for the customer, trust is a condition for exchange....

A survey of information-centric networking

The information-centric networking (ICN) concept is a significant common approach of several future Internet research activities. The approach leverages in-network caching, multiparty communication through replication, and interaction models decoupling...

A Review of Facebook Research in the Social Sciences

With over 800 million active users, Facebook is changing the way hundreds of millions of people relate to one another and share information. A rapidly growing body of research has accompanied the meteoric rise of Facebook as social scientists assess the...

Biodegradable synthetic polymers: Preparation, functionalization and biomedical application

Biodegradable polymers have been widely used and have greatly promoted the development of biomedical fields because of their biocompatibility and biodegradability. The development of biotechnology and medical technology has set higher requirements for...

High-efficiency inverted dithienogermole-thienopyrrolodione-based polymer solar cells

Cephas E. Small, Jegadesan Subbiah, Chad M. Amb, Sai‐Wing Tsang, Tzung-Han Lai, Franky So

The oyster genome reveals stress adaptation and complexity of shell formation

The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, the Mollusca. Here we report the sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy, along with...

The Economic Design of Control Charts: A Unified Approach

The choice of control chart parameters—sample size, sampling interval, and control limits—is considered from an economic point of view. A general process model is considered, and the hourly cost function is derived. This cost function simplifies when...

Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial.

Summary Background Pazopanib, a multitargeted tyrosine kinase inhibitor, has single-agent activity in patients with advanced non-adipocytic soft-tissue sarcoma. We investigated the eff ect of pazopanib on progression-free survival in patients with metastatic...

Hyperspectral Unmixing Overview: Geometrical, Statistical, and Sparse Regression-Based Approaches

Imaging spectrometers measure electromagnetic energy scattered in their instantaneous field view in hundreds or thousands of spectral channels with higher spectral resolution than multispectral cameras. Imaging spectrometers are therefore often referred...

Cultural studies : theory and practice

Chris Barker, Paul E. Willis

Smoking and lung function of Lung Health Study participants after 11 years.

spirometry in 77.4% of surviving participants who enrolled in a nal clinical centers for reassessment approximately 11 years long-term follow-up study. Those not enrolling tended to be after their enrollment. This report details the results of pulyounger...

The Modified Gauss-Newton Method for the Fitting of Non-Linear Regression Functions by Least Squares*

The experimental scientist is frequently faced with the task of determining the functional relation between a 'response', y and a number of 'inputs', x , x2, . * * , x, with the help of empirical data. Often the mathematical form of the functional relation...

Oral Antidiabetic Agents

Andrew J. Krentz, Clifford J. Bailey

Mitochondria and cancer

Contrary to conventional wisdom, functional mitochondria are essential for the cancer cell. Although mutations in mitochondrial genes are common in cancer cells, they do not inactivate mitochondrial energy metabolism but rather alter the mitochondrial...

Intact epithelial barrier function is critical for the resolution of alveolar edema in humans

Within 15 min of endotracheal intubation, the resolution of pulmonary edema was studied over the next 12 h in 34 mechanically ventilated patients by (1) serial measurements of the alveolar-arterial oxygen difference, (2) the extent of edema on the initial...

Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

Roughly half the world's population live in dengue-endemic countries, but no vaccine is licensed. We investigated the efficacy of a recombinant, live, attenuated tetravalent dengue vaccine.

2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association.

2012 focused update of the ESC Guidelines for the management of atrial fibrillation : An update of the 2010 ESC Guidelines for the management of atrial fibrillation: Developed with the special contribution of the European Heart Rhythm Association

Brodalumab, an Anti-Interleukin-17-Receptor Antibody for Psoriasis

Background In this phase 2, randomized, double-blind, placebo-controlled, dose-ranging study, we assessed the efficacy and safety of brodalumab (AMG 827), a human anti–interleukin-17–receptor monoclonal antibody, for the treatment of moderate-to-severe...

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

Objective: To examine the global prevalence and major risk factors for diabetic retinopathy (DR) and vision-threatening diabetic retinopathy (VTDR) among people with diabetes. Research Design and Methods: A pooled analysis using individual participant...

Particle Morphology and Density Characterization by Combined Mobility and Aerodynamic Diameter Measurements. Part 1: Theory

Different on-line submicron particle sizing techniques report different “equivalent diameters.” For example, differential mobility analyzers (DMAs) report electrical mobility diameter (dm), while a number of recently developed instruments (such as...

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

E. Sander Connolly, Alejandro A. Rabinstein, J. Ricardo Carhuapoma, Colin P. Derdeyn, Jacques E. Dion, Randall T. Higashida, Brian L. Hoh, Catherine J. Kirkness, Andrew M. Naidech, Christopher S. Ogilvy, Aman B. Patel, B. Gregory Thompson, Paul Vespa

Controllability and Stabilizability Theory for Linear Partial Differential Equations: Recent Progress and Open Questions

This paper is an assessment of the current state of controllability and observability theories for linear partial differential equations, summarizing existing results and indicating open problems in the area. The emphasis is placed on hyperbolic and parabolic...

On the LASSO and its Dual

Proposed by Tibshirani, the least absolute shrinkage and selection operator (LASSO) estimates a vector of regression coefficients by minimizing the residual sum of squares subject to a constraint on the l 1-norm of the coefficient vector. The LASSO estimator...

Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome

OBJECTIVES: This revised clinical practice guideline, intended for use by primary care clinicians, provides recommendations for the diagnosis and management of the obstructive sleep apnea syndrome (OSAS) in children and adolescents. This practice guideline...

Molecular mechanisms of cisplatin resistance

Lorenzo Galluzzi, Laura Senovilla, Ilio Vitale, Judith Michels, Isabelle Martins, Oliver Kepp, Maria Castedo, Guido Kroemer

CD-HIT

Summary: CD-HIT is a widely used program for clustering biological sequences to reduce sequence redundancy and improve the performance of other sequence analyses. In response to the rapid increase in the amount of sequencing data produced by the next-generation...

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number analysis to define genomic aberrations in a prospectively accrued clinical cohort (n = 142) of early (stage I and II) sporadic...

Bedside monitoring to adjust antiplatelet therapy for coronary stenting.

In the monitoring group, high platelet reactivity in patients taking clopidogrel (34.5% of patients) or aspirin (7.6%) led to the administration of an additional bolus of clopidogrel, prasugrel, or aspirin along with glycoprotein IIb/IIIa inhibitors during...

Adoptive immunotherapy for cancer: harnessing the T cell response

Nicholas P. Restifo, Mark E. Dudley, Steven A. Rosenberg

Increasing incidence of withholding and withdrawal of life support from the critically ill.

To determine whether limits to life-sustaining care are becoming more common, we attempted to quan­ tify the incidence of recommendations to withhold or withdraw life support from critically ill patients, to describe how patients respond to these recommendations,...

Immune Regulatory Function of B Cells

B cells are regarded for their capacity to produce antibody. However, recent advances in B cell biology have capitalized on old findings and demonstrated that B cells also release a broad variety of cytokines. As with T helper cells, B cells can be classified...

The insulin and insulin-like growth factor receptor family in neoplasia: an update

Although several early phase clinical trials raised enthusiasm for the use of insulin-like growth factor I receptor (IGF1R)-specific antibodies for cancer treatment, initial Phase III results in unselected patients have been disappointing. Further clinical...

Bayesian P-Splines

P-splines are an attractive approach for modelling nonlinear smooth effects of covariates within the generalized additive and varying coefficient models framework. In this paper we propose a Bayesian version for P-splines and generalize the approach for...

Planetary Candidates Observed by Kepler. III. Analysis of the First 16 Months of Data

New transiting planet candidates are identified in 16 months (2009 May‐2010 September) of data from the Kepler spacecraft. Nearly 5000 periodic transit-like signals are vetted against astrophysical and instrumental false positives yielding 1108 viable...

Preoperative Versus Postoperative Chemoradiotherapy for Locally Advanced Rectal Cancer: Results of the German CAO/ARO/AIO-94 Randomized Phase III Trial After a Median Follow-Up of 11 Years

Purpose Preoperative chemoradiotherapy (CRT) has been established as standard treatment for locally advanced rectal cancer after first results of the CAO/ARO/AIO-94 [Working Group of Surgical Oncology/Working Group of Radiation Oncology/Working Group...

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes

Personalized medicine is expected to benefit from combining genomic information with regular monitoring of physiological states by multiple high-throughput methods. Here, we present an integrative personal omics profile (iPOP), an analysis that combines...

From Marketing Mix to Relationship Marketing

Discusses the nature and sometimes negative consequences of the dominating marketing paradigm of today, marketing mix management, and furthermore discusses how modern research into, for example, industrial marketing and services marketing as well as customer...

Derivation and Validation of a Prognostic Model for Pulmonary Embolism

Rationale: An objective and simple prognostic model for patients with pulmonary embolism could be helpful in guiding initial intensity of treatment.Objectives: To develop a clinical prediction rule that accurately classifies patients with pulmonary embolism...

Network Tomography: Estimating Source-Destination Traffic Intensities from Link Data

The problem of estimating the node-to-node traffic intensity from repeated measurements of traffic on the links of a network is formulated and discussed under Poisson assumptions and two types of traffic-routing regimens: deterministic (a fixed known...

Do better schools lead to more growth? Cognitive skills, economic outcomes, and causation

We develop a new metric for the distribution of educational achievement across countries that can further track the cognitive skill distribution within countries and over time. Cross-country growth regressions generate a close relationship between educational...

A Yolk-Shell Design for Stabilized and Scalable Li-Ion Battery Alloy Anodes

Silicon is regarded as one of the most promising anode materials for next generation lithium-ion batteries. For use in practical applications, a Si electrode must have high capacity, long cycle life, high efficiency, and the fabrication must be industrially...

Genome-Wide Fetal Aneuploidy Detection by Maternal Plasma DNA Sequencing

OBJECTIVE: To prospectively determine the diagnostic accuracy of massively parallel sequencing to detect whole chromosome fetal aneuploidy from maternal plasma. METHODS: Blood samples were collected in a prospective, blinded study from 2,882 women undergoing...

Cobalt catalysts for the coupling of CO2 and epoxides to provide polycarbonates and cyclic carbonates

This comprehensive tutorial review focuses on well-defined cobalt complexes that serve as homogeneous catalysts for the production of polycarbonates and cyclic carbonates from the coupling of carbon dioxide and epoxides. Special considerations are given...

Coherent States, Wavelets and Their Generalizations

A survey of the theory of coherent states, wavelets, and some of their generalizations, emphasizing mathematical structures. Starting from the standard theory of coherent states over Lie groups, the authors generalize the formalism by associating coherent...

Iterative Reconstruction Technique for Reducing Body Radiation Dose at CT: Feasibility Study

OBJECTIVE. The purpose of this study was to evaluate the image noise, low-contrast resolution, image quality, and spatial resolution of adaptive statistical iterative reconstruction in low-dose body CT.MATERIALS AND METHODS. Adaptive statistical iterative...

An Exponential Family of Probability Distributions for Directed Graphs

Directed graph (or digraph) data arise in many fields, especially in contemporary research on structures of social relationships. We describe an exponential family of distributions that can be used for analyzing such data. A substantive rationale for...

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

Suzanne L. Topalian, Charles G. Drake, Drew M. Pardoll

The GENCODE v7 catalog of human long noncoding RNAs

Thomas Derrien, Rory Johnson, Giovanni Bussotti, Andrea Tanzer, Sarah Djebali, Hagen Tilgner, Gregory Guernec, David Martin, Angelika Merkel, David G. Knowles, Julien Lagarde, Lavanya Veeravalli, Xiaoan Ruan, Yijun Ruan, Timo Lassmann, Piero Carninci, Leonard Lipovich, Jose M. Gonzalez, Carrie A. Davis, Ramin Shiekhattar, Thomas R. Gingeras, Tim Hubbard, Cedric Notredame, Jennifer Harrow, Roderic Guigó

ACR Guidance Document for Safe MR Practices: 2007

Emanuel Kanal, A. James Barkovich, Charlotte Bell, James P. Borgstede, Jerry Froelich, Tobias Gilk, J. Rod Gimbel, John Gosbee, Ellisa Kuhni-Kaminski, James W. Lester, John A. Nyenhuis, Yoav Parag, Daniel J. Schaefer, Elizabeth A. Sebek-Scoumis, Jeffrey C. Weinreb, Loren A. Zaremba, Pamela A. Wilcox, Leonard Lucey, Nancy Sass

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Jens Lohr, Petar Stojanov, Michael S. Lawrence, Daniel Auclair, Bjoern Chapuy, Carrie Sougnez, Peter Cruz-Gordillo, Birgit Knoechel, Yan W. Asmann, Susan L. Slager, Anne J. Novak, Ahmet Dogan, Stephen M. Ansell, Brian K. Link, Lihua Zou, Joshua Gould, Gordon Saksena, Nicolas Stransky, Claudia Rangel-Escareño, Juan Carlos Fernandez-Lopez, Alfredo Hidalgo-Miranda, Jorge Melendez-Zajgla, Enrique Hernández-Lemus, Angela Schwarz-Cruz y Celis, Ivan Imaz-Rosshandler, Akinyemi I. Ojesina, Joonil Jung, Chandra Sekhar Pedamallu, Eric S. Lander, Thomas M. Habermann, James R. Cerhan, Margaret A. Shipp, Gad Getz, Todd R. Golub

Sequence analysis of mutations and translocations across breast cancer subtypes

Shantanu Banerji, Kristian Cibulskis, Claudia Rangel-Escareño, Kristin K. Brown, Scott L. Carter, Abbie M. Frederick, Michael S. Lawrence, Andrey Sivachenko, Carrie Sougnez, Lihua Zou, Maria L. Cortés, Juan Carlos Fernandez-Lopez, Shouyong Peng, Kristin Ardlie, Daniel Auclair, Verónica Bautista-Piña, Fujiko Duke, Joshua M. Francis, Joonil Jung, Antonio Maffuz-Aziz, Robert C. Onofrio, Melissa Parkin, Nam H. Pho, Valeria Quintanar-Jurado, Alex H. Ramos, Rosa Rebollar-Vega, Sergio Rodríguez-Cuevas, Sandra Romero-Cordoba, Steven E. Schumacher, Nicolas Stransky, Kristin Thompson, Laura Uribe-Figueroa, José Baselga, Rameen Beroukhim, Kornelia Polyak, Dennis C. Sgroi, Andrea L. Richardson, Gerardo Jimenez-Sanchez, Eric S. Lander, Stacey Gabriel, Levi A. Garraway, Todd R. Golub, Jorge Melendez-Zajgla, Alex Toker, Gad Getz, Alfredo Hidalgo-Miranda, Matthew Meyerson

Negligible Particle-Specific Antibacterial Activity of Silver Nanoparticles

For nearly a decade, researchers have debated the mechanisms by which AgNPs exert toxicity to bacteria and other organisms. The most elusive question has been whether the AgNPs exert direct “particle-specific” effects beyond the known antimicrobial...

A National Survey of End-of-life Care for Critically Ill Patients

In some intensive care units (ICUs), fewer patients who die now undergo attempts at cardiopulmonary resuscitation (CPR), and many more have life support actively withdrawn prior to death than did a decade ago. To determine the frequency of withdrawal...

Transcription factors: from enhancer binding to developmental control

Developmental progression is driven by specific spatiotemporal domains of gene expression, which give rise to stereotypically patterned embryos even in the presence of environmental and genetic variation. Views of how transcription factors regulate gene...

Leadership : enhancing the lessons of experience

Richard L. Hughes, Robert Ginnett, Gordon J. Curphy

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

Nancie M. Archin, Abigail L. Liberty, Kashuba Ad, Shailesh K. Choudhary, JoAnn D. Kuruc, Amanda M. Crooks, Daniel Parker, Elizabeth M. Anderson, Mary Kearney, Matthew C. Strain, Douglas D. Richman, Michael G. Hudgens, Ronald J. Bosch, John M. Coffin, Eron Jj, Daria J. Hazuda, David M. Margolis

Prevention and Treatment of Postoperative Nausea and Vomiting

Pain, nausea and vomiting are frequently listed by patients as their most important perioperative concerns. With the change in emphasis from an inpatient to outpatient hospital and office-based medical/surgical environment, there has been increased interest...

Graphene Photonics, Plasmonics, and Broadband Optoelectronic Devices

Graphene has been hailed as a wonderful material in electronics, and recently, it is the rising star in photonics, as well. The wonderful optical properties of graphene afford multiple functions of signal emitting, transmitting, modulating, and detection...

Quality of life changes in COPD patients treated with salmeterol.

Changes in health-related quality of life (HRQoL) were evaluated in patients with chronic obstructive pulmonary disease (COPO) following treatment with placebo, salmeterol 50 J,lg twice a day or 100 J,lg twice a day by metered-dose inhaler. Patients completed...

Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in normal subjects and in patients with COPD.

Early lactic acidosis during exercise and abnormal skeletal muscle function have been reported in chronic obstructive pulmonary disease (COPD) but a possible relationship between these two abnormalities has not been evaluated. The purpose of this study...

Pressure-Volume Curve of Total Respiratory System in Acute Respiratory Failure: Computed Tomographic Scan Study

To investigate the relationship between lung anatomy and pulmonary mechanics in acute respiratory failure (ARF), 20 patients with ARF underwent computerized tomography (CT) at 3 levels of positive end-expiratory pressure (PEEP) (5,10, and 15 cm H2O) ....

An Error-Components Model for Prediction of County Crop Areas Using Survey and Satellite Data

Knowledge of the area under different crops is important to the U.S. Department of Agriculture. Sample surveys have been designed to estimate crop areas for large regions, such as crop-reporting districts, individual states, and the United States as a...

Microsoft Kinect Sensor and Its Effect

Recent advances in 3D depth cameras such as Microsoft Kinect sensors (www.xbox.com/en-US/kinect) have created many opportunities for multimedia computing. The Kinect sensor lets the computer directly sense the third dimension (depth) of the players and...

The Multivariate Analysis of Qualitative Data: Interactions among Multiple Classifications

For the m-way contingency table, we discuss both the direct estimation of the multiplicative interactions among the m variables, and the indirect testing of hypotheses pertaining to these interactions. We consider, among other things, hierarchical hypotheses...

Designing nanostructured Si anodes for high energy lithium ion batteries

Si electrode failure mechanisms: (a) Material pulverization. (b) Continuous SEI growth. (c) Morphology and volume change of the entire Si electrode.► We reviewed recent research progress on Si based high performance anode for lithium ion batteries....

Comparison of Methods for Image Analysis on cDNA Microarray Data

Microarrays are part of a new class of biotechnologies which allow the monitoring of expression levels for thousands of genes simultaneously. Image analysis is an important aspect of microarray experiments, one that can have a potentially large impact...

Doxil® — The first FDA-approved nano-drug: Lessons learned

Doxil®, the first FDA-approved nano-drug (1995), is based on three unrelated principles: (i) prolonged drug circulation time and avoidance of the RES due to the use of PEGylated nano-liposomes; (ii) high and stable remote loading of doxorubicin driven...

The cellular and signaling networks linking the immune system and metabolism in disease

It is now recognized that obesity is driving the type 2 diabetes epidemic in Western countries. Obesity-associated chronic tissue inflammation is a key contributing factor to type 2 diabetes and cardiovascular disease, and a number of studies have clearly...

The Fitting of Straight Lines when Both Variables are Subject to Error

Consider the situation where X and Y are related by Y = α + βX, where α and β are unknown and where we observe X and Y with error, i.e., we observe x = X + u and y = Y + v. Assume that Eu = Ev = 0 and that the errors (u and v) are...

MetaboAnalyst 2.0—a comprehensive server for metabolomic data analysis

Jianguo Xia, Rupasri Mandal, Igor Sinelnikov, David Broadhurst, David S. Wishart

Theories of Reproduction and Resistance in the New Sociology of Education: A Critical Analysis

In the past ten years radical educators have developed several theories around the notions of reproduction and resistance. In this article, Henry Giroux critically analyzes the major positions of these theories, finding them inadequate as a foundation...

A IDENTIDADE CULTURAL NA PÓS – MODERNIDADE

This paper aims to understand and identify issues regarding cultural identity in postmodernity, resorting to literature reviews, which reflects conceptual discussions about the subject, education, science, culture and man’s relationship in postmodern...

An Improved Method for Numerical Inversion of Laplace Transforms

An improved procedure for numerical inversion of Laplace transforms is proposed based on accelerating the convergence of the Fourier series obtained from the inversion integral using the trapezoidal rule. When the full complex series is used, at each...

A Multiresponsive, Shape‐Persistent, and Elastic Supramolecular Polymer Network Gel Constructed by Orthogonal Self‐Assembly

Xuzhou Yan, Donghua Xu, Xiaodong Chi, Jianzhuang Chen, Shengyi Dong, Xia Ding, Yihua Yu, Feihe Huang

Diversity as a Concept and its Measurement

munities is defined and is shown to be equivalent to stochastic ordering. Also, the sensitivity of an index to rare species is developed, culminating in a crossing-point theorem and a response theory to perturbations. Diversity decompositions, analogous...

In vivo Genome Editing Using High Efficiency TALENS.

Victoria M. Bedell, Ying Wang, Jarryd M. Campbell, Tanya L. Poshusta, Colby G. Starker, Randall G. Krug, Wenfang Tan, Sumedha G. Penheiter, Alvin C.H. Ma, Anskar Y. H. Leung, Scott C. Fahrenkrug, Daniel F. Carlson, Daniel F. Voytas, Karl J. Clark, Jeffrey J. Essner, Stephen C. Ekker

Dynamic Capabilities, Social Capital, and Rent Appropriation: Ties that Split Pies

Who reaps the fruits of a dynamic capability? We argue that while social capital is essential for the acquisition, integration, and release of resources at the core of a dynamic capability, actors can also use social capital for personal gain. Thus, social...

Central and Peripheral Circadian Clocks in Mammals

The circadian system of mammals is composed of a hierarchy of oscillators that function at the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell-autonomous circadian oscillator throughout the body, yet this clock system...

SYNTHESIS OF A LAYERED MEDIUM FROM ITS ACOUSTIC TRANSMISSION RESPONSE

A direct (noniterative) method is presented to determine an acoustic layered medium from the seismogram due to a time‐limited plane wave incident from the lower halfspace. It is shown that one side of the autocorrelation of the seismogram due to an...

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

The umpolung strategy encompasses all the methods that make organic molecules react in an inverse manner compared to their innate polarity-driven reactivity. This concept entered the field of organocatalysis when it was recognized that N-heterocyclic...

The Role of Driving Energy and Delocalized States for Charge Separation in Organic Semiconductors

The electron-hole pair created via photon absorption in organic photoconversion systems must overcome the Coulomb attraction to achieve long-range charge separation. We show that this process is facilitated through the formation of excited, delocalized...

Occurrence of pharmaceutical compounds in urban wastewater: Removal, mass load and environmental risk after a secondary treatment—A review

This review focuses on 118 pharmaceuticals, belonging to seventeen different therapeutic classes, detected in raw urban wastewater and effluent from an activated sludge system, a usual treatment adopted for urban wastewaters worldwide prior to final discharge...

A Community-based Study of the Epidemiology of Asthma: Incidence Rates, 1964–1983

To determine whether the incidence of asthma had increased in Rochester, Minnesota, from January 1, 1964 through December 31, 1983, we used a population-based computer-linked medical diagnosis system to identify individual medical records with diagnoses...

A High-Coverage Genome Sequence from an Archaic Denisovan Individual

We present a DNA library preparation method that has allowed us to reconstruct a high-coverage (30x) genome sequence of a Denisovan, an extinct relative of Neandertals. The quality of this genome allows a direct estimation of Denisovan heterozygosity...

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Christian M. Metallo, Paulo A. Gameiro, Eric L. Bell, Katherine R. Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M. Jewell, Zachary R. Johnson, Darrell J. Irvine, Leonard Guarente, Joanne K. Kelleher, Matthew G. Vander Heiden, Othon Iliopoulos, Gregory Stephanopoulos

« Prev. Next »
First ... 2 3 4 5 6 7 8 9 10 11 12 13 ... Last

© 2016-2018 CiteWeb.info — WorldWeb citation database

Up ↑