CiteWeb

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Publications in 2012

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Reference Equations for the Six-Minute Walk in Healthy Adults

In order to establish reference equations for prediction of the total distance walked during six minutes (6MWD) for healthy adults, we administered the standardized 6-min walk test to 117 healthy men and 173 healthy women, aged 40 to 80 yr. Oxygen saturation...

Prevention of VTE in Nonsurgical Patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

Funding/Support: The Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines received support from the National Heart, Lung, and Blood Institute [R13 HL104758] and Bayer...

A Tale of Two Time Scales

It is a common practice in finance to estimate volatility from the sum of frequently sampled squared returns. However, market microstructure poses challenges to this estimation approach, as evidenced by recent empirical studies in finance. The present...

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.

Many different definitions for multidrug-resistant (MDR), extensively drug-resistant (XDR) and pandrug-resistant (PDR) bacteria are being used in the medical literature to characterize the different patterns of resistance found in healthcare-associated,...

Gold Nanoparticles in Chemical and Biological Sensing

Krishnendu Saha, Sarit S. Agasti, Chaekyu Kim, Xiaoning Li, Vincent M. Rotello

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

S um m a r y A previously unknown coronavirus was isolated from the sputum of a 60-year-old man who presented with acute pneumonia and subsequent renal failure with a fatal outcome in Saudi Arabia. The virus (called HCoV-EMC) replicated readily in cell...

Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer

Background The anti–human epidermal growth factor receptor 2 (HER2) humanized monoclonal antibody trastuzumab improves the outcome in patients with HER2-positive metastatic breast cancer. However, most cases of advanced disease eventually progress....

Sparse Principal Component Analysis

Principal component analysis (PCA) is widely used in data processing and dimensionality reduction. However, PCA suffers from the fact that each principal component is a linear combination of all the original variables, thus it is often difficult to interpret...

Cognition and Learning

Thomas H. Leahey

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against hypothermia and obesity. Recent data suggest that there are two distinct types of brown fat: classical brown fat derived from a myf-5 cellular lineage and UCP1-positive...

Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes

Of the 150 patients, 93% completed 12 months of follow-up. The proportion of patients with the primary end point was 12% (5 of 41 patients) in the medicaltherapy group versus 42% (21 of 50 patients) in the gastric-bypass group (P = 0.002)...

Signatures of Majorana Fermions in Hybrid Superconductor-Semiconductor Nanowire Devices

When a negatively charged electron meets a positron—its positively charged antiparticle—they annihilate each other in a flash of gamma rays. A Majorana fermion, on the other hand, is a neutral particle, which is its own antiparticle. No sightings...

Multivariate SPC Charts for Monitoring Batch Processes

The problem of using time-varying trajectory data measured on many process variables over the finite duration of a batch process is considered. Multiway principal-component analysis is used to compress the information contained in the data trajectories...

PartitionFinder: Combined Selection of Partitioning Schemes and Substitution Models for Phylogenetic Analyses

In phylogenetic analyses of molecular sequence data, partitioning involves estimating independent models of molecular evolution for different sets of sites in a sequence alignment. Choosing an appropriate partitioning scheme is an important step in most...

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

Natalie A. Molodecky, Ing Shian Soon, Doreen M. Rabi, William A. Ghali, Mollie C. Ferris, Greg Chernoff, Eric I. Benchimol, Gilaad G. Kaplan

Foundations of Intelligent Systems

Zbigniew W. Raś, Andrzej Skowron

Diffusion-Weighted MRI in the Body: Applications and Challenges in Oncology

OBJECTIVE: In this article, we present the basic principles of diffusion-weighted imaging (DWI) that can aid radiologists in the qualitative and quantitative interpretation of DW images. However, a detailed discussion of the physics of DWI is beyond the...

Nuclear Ribosomal Internal Transcribed Spacer (ITS) Region as a Universal DNA Barcode Marker for Fungi

Six DNA regions were evaluated as potential DNA barcodes for Fungi, the second largest kingdom of eukaryotic life, by a multinational, multilaboratory consortium. The region of the mitochondrial cytochrome c oxidase subunit 1 used as the animal barcode...

Handbook of health psychology

Andrew Baum, Tracey A. Revenson, Jerome E. Singer

Thyroid Cancer after Exposure to External Radiation: A Pooled Analysis of Seven Studies

The thyroid gland of children is especially vulnerable to the carcinogenic action of ionizing radiation. To provide insights into various modifying influences on risk, seven major studies with organ doses to individual subjects were evaluated. Five cohort...

Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document

The aim of the current Valve Academic Research Consortium (VARC)-2 initiative was to revisit the selection and definitions of transcatheter aortic valve implantation (TAVI)clinical endpoints to make them more suitable to the present and future needs of...

Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer

Background The role of neoadjuvant chemoradiotherapy in the treatment of patients with esophageal or esophagogastric-junction cancer is not well established. We compared chemoradiotherapy followed by surgery with surgery alone in this patient population....

Dark Matter Results from 225 Live Days of XENON100 Data

: We report on a search for particle dark matter with the XENON100 experiment, operated at the Laboratori Nazionali del Gran Sasso (LNGS) for 13 months during 2011 and 2012. XENON100 features an ultra-low electromagnetic background of (5.3\pm0.6)\times10^-3...

Unmasking Multivariate Outliers and Leverage Points

Detecting outliers in a multivariate point cloud is not trivial, especially when there are several outliers. The classical identification method does not always find them, because it is based on the sample mean and covariance matrix, which are themselves...

The Bayesian Lasso

The Lasso estimate for linear regression parameters can be interpreted as a Bayesian posterior mode estimate when the regression parameters have independent Laplace (i.e., double-exponential) priors. Gibbs sampling from this posterior is possible using...

Bariatric Surgery versus Conventional Medical Therapy for Type 2 Diabetes

Results At 2 years, diabetes remission had occurred in no patients in the medical-therapy group versus 75% in the gastric-bypass group and 95% in the biliopancreatic-diversion group (P<0.001 for both comparisons). Age, sex, baseline BMI,...

Leishmaniasis Worldwide and Global Estimates of Its Incidence

As part of a World Health Organization-led effort to update the empirical evidence base for the leishmaniases, national experts provided leishmaniasis case data for the last 5 years and information regarding treatment and control in their respective countries...

Nineteen Dubious Ways to Compute the Exponential of a Matrix

In principle, the exponential of a matrix could be computed in many ways. Methods involving approximation theory, differential equations, the matrix eigenvalues, and the matrix characteristic polynomial have been proposed. In practice, consideration of...

Bayesian Model Averaging for Linear Regression Models

We consider the problem of accounting for model uncertainty in linear regression models. Conditioning on a single selected model ignores model uncertainty, and thus leads to the underestimation of uncertainty when making inferences about quantities of...

Na-ion batteries, recent advances and present challenges to become low cost energy storage systems

Energy production and storage have become key issues concerning our welfare in daily life. Present challenges for batteries are twofold. In the first place, the increasing demand for powering systems of portable electronic devices and zero-emission vehicles...

Parametric Empirical Bayes Inference: Theory and Applications

This article reviews the state of multiparameter shrinkage estimators with emphasis on the empirical Bayes viewpoint, particularly in the case of parametric prior distributions. Some successful applications of major importance are considered. Recent results...

Sparse Solution of Underdetermined Systems of Linear Equations by Stagewise Orthogonal Matching Pursuit

Finding the sparsest solution to underdetermined systems of linear equations y = Φ x is NP-hard in general. We show here that for systems with “typical”/“random” Φ, a good approximation to the sparsest solution is obtained by applying a fixed...

Everolimus in Postmenopausal Hormone- Receptor-Positive Advanced Breast Cancer

Background Resistance to endocrine therapy in breast cancer is associated with activation of the mammalian target of rapamycin (mTOR) intracellular signaling pathway. In early studies, the mTOR inhibitor everolimus added to endocrine therapy showed antitumor...

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

The human genome contains many thousands of long noncoding RNAs (lncRNAs). While several studies have demonstrated compelling biological and disease roles for individual examples, analytical and experimental approaches to investigate these genes have...

Microvascular blood flow is altered in patients with sepsis.

Microvascular blood flow alterations are frequent in animal models of sepsis and may impair tissue oxygenation. We hypothesized that alterations of the microcirculation are present in patients with sepsis. We used an orthogonal polarization spectral imaging...

Student Success in College: Creating Conditions That Matter.

George D. Kuh, Jillian Kinzie, John H. Schuh, Elizabeth J. Whitt

Demographic Correlates of DSM-IV Major Depressive Disorder among Older African Americans, Black Caribbeans, and Non-Hispanic Whites: Results from the National Survey of American Life

Patient AccessPatients and/or caregivers may access this content for use in relation to their own personal healthcare or that of a family member only. Terms and conditions will apply.

Review of fast pyrolysis of biomass and product upgrading

This paper provides an updated review on fast pyrolysis of biomass for production of a liquid usually referred to as bio-oil. The technology of fast pyrolysis is described including the major reaction systems. The primary liquid product is characterised...

Learning to Classify Text Using Support Vector Machines

Based on ideas from Support Vector Machines (SVMs), Learning To Classify Text Using Support Vector Machines presents a new approach to generating text classifiers from examples. The approach combines high performance and efficiency with theoretical understanding...

Maximum likelihood estimates of linear dynamic systems

H. E. Rauch, Charlotte Striebel, F. Tung

NEURAL EXCITABILITY, SPIKING AND BURSTING

Bifurcation mechanisms involved in the generation of action potentials (spikes) by neurons are reviewed here. We show how the type of bifurcation determines the neuro-computational properties of the cells. For example, when the rest state is near a saddle-node...

Age and ageing

Lifespan developmental psychology is based primarily on heterosexual samples. In this chapter we consider the issues faced by lesbian, gay and bisexual (LGB) people during different stages of life. We consider the role of generational effects in determining...

Extreme Learning Machine for Regression and Multiclass Classification

Due to the simplicity of their implementations, least square support vector machine (LS-SVM) and proximal support vector machine (PSVM) have been widely used in binary classification applications. The conventional LS-SVM and PSVM cannot be used in regression...

Obstructive Sleep Apnea Is Independently Associated with Insulin Resistance

Epidemiological studies have implicated obstructive sleep apnea (OSA) as an independent comorbid factor in cardiovascular and cerebrovascular diseases. It is postulated that recurrent episodes of occlusion of upper airways during sleep result in pathophysiological...

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of recommendations for the definition of distinct cell death morphologies and for the appropriate use of cell death-related terminology, including ‘apoptosis’, ‘necrosis’...

Biodiversity loss and its impact on humanity

The most unique feature of Earth is the existence of life, and the most extraordinary feature of life is its diversity. Approximately 9 million types of plants, animals, protists and fungi inhabit the Earth. So, too, do 7 billion people. Two decades ago,...

Antithrombotic Therapy for VTE Disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: AmericanCollege of Chest Physicians Evidence-Based Clinical PracticeGuidelines

Clive Kearon, Elie A. Akl, Anthony J. Comerota, Paolo Prandoni, Henri Bounameaux, Samuel Z. Goldhaber, Michael E. Nelson, Philip S. Wells, Michael K. Gould, Francesco Dentali, Mark A. Crowther, Susan R. Kahn

The UCSC Genome Browser database: extensions and updates 2011

Timothy R. Dreszer, Donna Karolchik, Ann S. Zweig, Angie S. Hinrichs, Brian J. Raney, Robert M. Kuhn, Laurence R. Meyer, Mathew Wong, Cricket A. Sloan, Kate R. Rosenbloom, Greg Roe, Brooke Rhead, Andy Pohl, Venkat S. Malladi, Chin H. Li, Katrina Learned, Vanessa Kirkup, Fan Hsu, Rachel A. Harte, Luvina Guruvadoo, Mary Goldman, Belinda Giardine, Pauline A. Fujita, Mark Diekhans, Melissa Cline, Hiram Clawson, Galt P. Barber, David Haussler, W. James Kent

American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults

Potentially inappropriate medications (PIMs) continue to be prescribed and used as first-line treatment for the most vulnerable of older adults, despite evidence of poor outcomes from the use of PIMs in older adults. PIMs now form an integral part of...

Measurement of Linear Dependence and Feedback between Multiple Time Series

Measures of linear dependence and feedback for multiple time series are defined. The measure of linear dependence is the sum of the measure of linear feedback from the first series to the second, linear feedback from the second to the first, and instantaneous...

Time Course and Recovery of Exacerbations in Patients with Chronic Obstructive Pulmonary Disease

Although exacerbations of chronic obstructive pulmonary disease (COPD) are associated with symptomatic and physiological deterioration, little is known of the time course and duration of these changes. We have studied symptoms and lung function changes...

Coupling of Substructures for Dynamic Analyses

A method for treating a complex structure as an assemblage of distinct regions, or substructures, is presented. Using basic mass and stiffness matrices for the substructures, together with conditions of geometrical compatibility along substructure boundaries,...

Choosing between logistic regression and discriminant analysis

Classifying an observation into one of several populations is discriminant analysis, or classification. Relating qualitative variables to other variables through a logistic cdf functional form is logistic regression. Estimators generated for one of these...

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagenomic data with whole-genome assemblies...

Tests for Parameter Instability in Regressions With I(1) Processes

This paper derives the large sample distributions of Lagrange multiplier tests for parameter instability against several alternatives of interest in the context of cointegrated regression models. The test statistics considered include the SupF test of...

Network Information Theory

This comprehensive treatment of network information theory and its applications provides the first unified coverage of both classical and recent results. With an approach that balances the introduction of new models and new coding techniques, readers...

Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation.

Several modalities of ventilatory support have been proposed to gradually withdraw patients from mechanical ventilation, but their respective effects on the outcome of weaning from mechanical ventilation are not known. We conducted a randomized trial...

Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses

For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional concepts in toxicology, in particular the dogma of “the dose makes the poison,” because EDCs can have effects at low doses that are not predicted by effects...

Model Selection and Accounting for Model Uncertainty in Graphical Models Using OCCAM's Window

We consider the problem of model selection and accounting for model uncertainty in high-dimensional contingency tables, motivated by expert system applications. The approach most used currently is a stepwise strategy guided by tests based on approximate...

Graphical Perception: Theory, Experimentation, and Application to the Development of Graphical Methods

The subject of graphical methods for data analysis and for data presentation needs a scientific foundation. In this article we take a few steps in the direction of establishing such a foundation. Our approach is based on graphical perception—the visual...

Radical Prostatectomy versus Observation for Localized Prostate Cancer

During the median follow-up of 10.0 years, 171 of 364 men (47.0%) assigned to radi cal prostatectomy died, as compared with 183 of 367 (49.9%) assigned to observation (hazard ratio, 0.88; 95% confidence...

Convexity and optimization in Banach spaces

Viorel Barbu, Theodor Precupanu

Tidal ventilation at low airway pressures can augment lung injury.

Intermittent positive pressure ventilation with large tidal volumes and high peak airway pressures can result in pulmonary barotrauma. In the present study, we examined the hypothesis that ventilation at very low lung volumes can also worsen lung injury...

Neural Information Processing

Tingwen Huang, Zhigang Zeng, Chuandong Li, Chi Sing Leung

Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms

DNA sequencing continues to decrease in cost with the Illumina HiSeq2000 generating up to 600Gb of paired-end 100 base reads in a ten-day run. Here we present a protocol for community amplicon sequencing on the HiSeq2000 and MiSeq Illumina platforms,...

Business intelligence and analytics: from big data to big impact

Business intelligence and analytics (BI&A) has emerged as an important area of study for both practitioners and researchers, reflecting the magnitude and impact of data-related problems to be solved in contemporary business organizations. This introduction...

Probabilistic topic models

Surveying a suite of algorithms that offer a solution to managing large document archives.

Computers And Thought

From the Publisher:Computers and Thought showcases the work of the scientists who not only defined the field of Artificial Intelligence, but who are responsible for having developed it into what it is today. Originally published in 1963, this collection...

Weight Loss Is a Reversible Factor in the Prognosis of Chronic Obstructive Pulmonary Disease

The objective of the study was to further unravel the prognostic significance of body weight changes in patients with COPD. Two survival analyses were performed: (1) a retrospective study, including 400 patients with COPD none of whom had received nutritional...

Consumer acceptance and use of information technology: extending the unified theory of acceptance and use of technology

This paper extends the unified theory of acceptance and use of technology (UTAUT) to study acceptance and use of technology in a consumer context. Our proposed UTAUT2 incorporates three constructs into UTAUT: hedonic motivation, price value, and habit....

Quantum Groups

Here is an introduction to the theory of quantum groups with emphasis on the spectacular connections with knot theory and Drinfeld's recent fundamental contributions. It presents the quantum groups attached to SL2 as well as the basic concepts of the...

Fluorescent indicators based on BODIPY

This critical review covers the advances made using the 4-bora-3a,4a-diaza-s-indacene (BODIPY) scaffold as a fluorophore in the design, synthesis and application of fluorescent indicators for pH, metal ions, anions, biomolecules, reactive oxygen species,...

Generalized Inverses, Ridge Regression, Biased Linear Estimation, and Nonlinear Estimation

A principal objective of this paper is to discuss a class of biased linear estimators employing generalized inverses. A second objective is to establish a unifying perspective. The paper exhibits theoretical properties shared by generalized inverse estimators,...

Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths

Background In the National Polyp Study (NPS), colorectal cancer was prevented by colonoscopic removal of adenomatous polyps. We evaluated the long-term effect of colonoscopic polypectomy in a study on mortality from colorectal cancer. Methods We included...

Screening for Prostate Cancer: U.S. Preventive Services Task Force Recommendation Statement

| Summary of Recommendation and Evidence | Rationale | Clinical Considerations |

High inflation pressure pulmonary edema: respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure

The respective roles of high pressure and high tidal volume to promote high airway pressure pulmonary edema are unclear. Positive end-expiratory pressure (PEEP) was shown to reduce lung water content in this type of edema, but its possible effects on...

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

Brian J. O’Roak, Laura Vives, Santhosh Girirajan, Emre Karakoc, Niklas Krumm, Bradley P. Coe, Roie Levy, Arthur Ko, Choli Lee, Joshua D. Smith, Emily H. Turner, Ian B. Stanaway, Benjamin Vernot, Maika Malig, Carl Baker, Beau Reilly, Joshua M. Akey, Elhanan Borenstein, Mark J. Rieder, Deborah A. Nickerson, Raphael Bernier, Jay Shendure, Evan E. Eichler

A metagenome-wide association study of gut microbiota in type 2 diabetes

Assessment and characterization of gut microbiota has become a major research area in human disease, including type 2 diabetes, the most prevalent endocrine disease worldwide. To carry out analysis on gut microbial content in patients with type 2 diabetes,...

Ridge Regression: Applications to Nonorthogonal Problems

This paper is an exposition of the use of ridge regression methods. Two examples from the literature are used as a base. Attention is focused on the RIDGE TRACE which is a two-dimensional graphical procedure for portraying the complex relationships in...

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

Ravid Straussman, Teppei Morikawa, Kevin Shee, Michal Barzily-Rokni, Zhi Rong Qian, Jinyan Du, Ashli Davis, Margaret M. Mongare, Joshua Gould, Dennie T. Frederick, Zachary A. Cooper, Paul B. Chapman, David B. Solit, Antoni Ribas, Roger S. Lo, Keith T. Flaherty, Shuji Ogino, Jennifer A. Wargo, Todd R. Golub

Calibration Estimators in Survey Sampling

This article investigates estimation of finite population totals in the presence of univariate or multivariate auxiliary information. Estimation is equivalent to attaching weights to the survey data. We focus attention on the several weighting systems...

A Suggestion for Using Powerful and Informative Tests of Normality

For testing that an underlying population is normally distributed the skewness and kurtosis statistics, fi and b2, and the D’ Agostino-Pearson K2 statistic that combines these two statistics have been shown to be powerful and informative tests. Their...

Global malaria mortality between 1980 and 2010: a systematic analysis

During the past decade, renewed global and national efforts to combat malaria have led to ambitious goals. We aimed to provide an accurate assessment of the levels and time trends in malaria mortality to aid assessment of progress towards these goals...

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

Highly pathogenic avian influenza A/H5N1 virus can cause morbidity and mortality in humans but thus far has not acquired the ability to be transmitted by aerosol or respiratory droplet (“airborne transmission”) between humans. To address the concern...

Computer Aided Design of Experiments

A computer oriented method which assists in the construction of response surface type experimental plans is described. It takes into account constraints met in practice that standard procedures do not consider explicitly. The method is a sequential one...

Corporate Social Reporting: A Rebuttal of Legitimacy Theory

Various rationales have been advanced to explain the phenomenon of corporate social reporting. Among these has been legitimacy theory which posits that corporate disclosures are made as reactions to environmental factors and in order to legitimise corporate...

Global physical activity levels: surveillance progress, pitfalls, and prospects

To implement effective non-communicable disease prevention programmes, policy makers need data for physical activity levels and trends. In this report, we describe physical activity levels worldwide with data for adults (15 years or older) from 122 countries...

Tandem polymer solar cells featuring a spectrally matched low-bandgap polymer

Letian Dou, Jingbi You, Jun Yang, Chieh-Wei Chen, Youjun He, Seiichiro Murase, Tom Moriarty, Keith Emery, Gang Li, Yang Yang

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

Background In the RV144 trial, the estimated efficacy of a vaccine regimen against human immunodeficiency virus type 1 (HIV-1) was 31.2%. We performed a case–control analysis to identify antibody and cellular immune correlates of infection risk. Methods...

Cluster analysis and clinical asthma phenotypes

Rationale—Heterogeneity in asthma expression is multidimensional, including variability in clinical, physiologic, and pathologic parameters. Classification requires consideration of these disparate domains in a unified model. Objectives—To explore...

Linked data: evoluving the web into a global data space

The World Wide Web has enabled the creation of a global information space comprising linked documents. As the Web becomes ever more enmeshed with our daily lives, there is a growing desire for direct access to raw data not currently available on the Web...

Risk factors for central and obstructive sleep apnea in 450 men and women with congestive heart failure.

In previous analyses of the occurrence of central (CSA) and obstructive sleep apnea (OSA) in patients with congestive heart failure (CHF), only men were studied and risk factors for these disorders were not well characterized. We therefore analyzed risk...

lavaan: An R Package for Structural Equation Modeling

Structural equation modeling (SEM) is a vast field and widely used by many applied researchers in the social and behavioral sciences. Over the years, many software packages for structural equation modeling have been developed, both free and commercial....

Estimation of the Generalized Extreme- Value Distribution by the Method of Probability-Weighted Moments

We use the method of probability-weighted moments to derive estimators of the parameters and quantiles of the generalized extreme-value distribution. We investigate the properties of these estimators in large samples, via asymptotic theory, and in small...

STATISTICAL MODELS FOR INTERPRETING AEROMAGNETIC DATA

A mathematical basis for the application of power spectrum analysis to aeromagnetic map interpretation is developed. An ensemble of blocks of varying depth, width, thickness, and magnetization is considered as a statistical model. With the use of the...

The Cultural Logic of Late Capitalism

Fredric. Postmodernism Jameson

Continuous support for women during childbirth

Historically women have been attended and supported by other women during labour and birth. However in many countries, as more women are giving birth in hospital rather than at home, continuous support during labour has become the exception rather than...

Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

We identified at least one somatic alteration in 97.3% of the patients. We found that internal tandem duplication in FLT3 (FLT3-ITD), partial tandem duplication in MLL (MLL-PTD), and mutations in ASXL1 and PHF6 were associated with reduced overall survival...

The Selection of Prior Distributions by Formal Rules

Subjectivism has become the dominant philosophical foundation for Bayesian inference. Yet in practice, most Bayesian analyses are performed with so-called “noninformative” priors, that is, priors constructed by some formal rule. We review the plethora...

Statistical Models for Earthquake Occurrences and Residual Analysis for Point Processes

This article discusses several classes of stochastic models for the origin times and magnitudes of earthquakes. The models are compared for a Japanese data set for the years 1885–1980 using likelihood methods. For the best model, a change of time scale...

Estimation Methods for Models of Spatial Interaction

Autoregressive models for spatial interaction have been proposed by several authors (Whittle [15] and Mead [11], for example). In the past, computational difficulties with the ML approach have led to the use of alternative estimators. In this article,...

Robust Statistical Modeling Using the t Distribution

The t distribution provides a useful extension of the normal for statistical modeling of data sets involving errors with longer-than-normal tails. An analytical strategy based on maximum likelihood for a general model with multivariate t errors is suggested...

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