CiteWeb

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Publications in 2012

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The Robust Inference for the Cox Proportional Hazards Model

We derive the asymptotic distribution of the maximum partial likelihood estimator β for the vector of regression coefficients β under a possibly misspecified Cox proportional hazards model. As in the parametric setting, this estimator β converges to...

Filtering via Simulation: Auxiliary Particle Filters

The full-text of this article is not available in ORA at this time. Citation: Pitt, M. K. & Shephard, N. (1999). 'Filtering via simulation: auxiliary particle filters', Journal of the American Statistical Association, 94(446), 590-599.

Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests under Nonstandard Conditions

Large sample properties of the likelihood function when the true parameter value may be on the boundary of the parameter space are described. Specifically, the asymptotic distribution of maximum likelihood estimators and likelihood ratio statistics are...

Carbon dioxide capture in metal-organic frameworks.

Kenji Sumida, David L. Rogow, Jarad A. Mason, Thomas M. McDonald, Eric D. Bloch, Zoey R. Herm, Tae-Hyun Bae, Jeffrey R. Long

EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma

Michel Ducreux, Riccardo Lencioni, Am Di Bisceglie, Pr Galle, J-F. Dufour, T. F. Greten, Eric Raymond, Tania Roskams, T. de Baere, Mazzaferro, M Bernardi, Jordi Bruix, M. Colombo, Andrew X. Zhu

COASTAL MARINE EUTROPHICATION: A DEFINITION, SOCIAL CAUSES, AND FUTURE CONCERNS

There is a need in the marine research and management communities for a clear operational definition of the term, eutrophication. I propose the following: This definition is consistent with historical usage and emphasizes that eutrophication is a process,...

Interventions for preventing falls in older people living in the community

As people get older, they may fall more often for a variety of reasons including problems with balance, poor vision, and dementia. Up to 30% may fall in a year. Although one in five falls may require medical attention, less than one in 10 results in...

Procedures for Detecting Outlying Observations in Samples

Procedures are given for determining statistically whether the highest observation, the lowest observation, the highest and lowest observations, the two highest observations, the two lowest observations, or more of the observations in the sample are statistical...

Psychology of reading

Keith Rayner, Alexander Pollatsek, Jane Ashby, Charles Clifton

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

Non-fatal health outcomes from diseases and injuries are a crucial consideration in the promotion and monitoring of individual and population health. The Global Burden of Disease (GBD) studies done in 1990 and 2000 have been the only studies to quantify...

Efficient Hybrid Solar Cells Based on Meso-Superstructured Organometal Halide Perovskites

The energy costs associated with separating tightly bound excitons, photo-generated electron-hole pairs, and extracting free charges from highly disordered low mobility networks represent fundamental losses for many low-cost photovoltaic technologies....

Maximum Likelihood Approaches to Variance Component Estimation and to Related Problems

Recent developments promise to increase greatly the popularity of maximum likelihood (ml) as a technique for estimating variance components. Patterson and Thompson (1971) proposed a restricted maximum likelihood (reml) approach which takes into account...

Programming Massively Parallel Processors: A Hands-on Approach

Programming Massively Parallel Processors: A Hands-on Approach shows both student and professional alike the basic concepts of parallel programming and GPU architecture. Various techniques for constructing parallel programs are explored in detail. Case...

Sequential Monte Carlo Methods for Dynamic Systems

We provide a general framework for using Monte Carlo methods in dynamic systems and discuss its wide applications. Under this framework, several currently available techniques are studied and generalized to accommodate more complex features. All of these...

ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC)

ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation : the Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC)

Smearing Estimate: A Nonparametric Retransformation Method

The smearing estimate is proposed as a nonparametric estimate of the expected response on the untransformed scale after fitting a linear regression model on a transformed scale. The estimate is consistent under mild regularity conditions, and usually...

Estimation of Dynamic Models with Error Components

Observations on N cross-section units at T time points are used to estimate a simple statistical model involving an autoregressive process with an additive term specific to the unit. Different assumptions about the initial conditions are (a) initial state...

Antithrombotic Therapy for VTE Disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

Funding/Support: The Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines received support from the National Heart, Lung, and Blood Institute [R13 HL104758] and Bayer...

Thirteen Ways to Look at the Correlation Coefficient

In 1885, Sir Francis Galton first defined the term “regression” and completed the theory of bivariate correlation. A decade later, Karl Pearson developed the index that we still use to measure correlation, Pearson's r. Our article is written in recognition...

P-SV wave propagation in heterogeneous media: Velocity‐stress finite‐difference method

I present a finite‐difference method for modeling P-SV wave propagation in heterogeneous media. This is an extension of the method I previously proposed for modeling SH-wave propagation by using velocity and stress in a discrete grid. The two components...

Overview of the High Efficiency Video Coding (HEVC) Standard

High Efficiency Video Coding (HEVC) is currently being prepared as the newest video coding standard of the ITU-T Video Coding Experts Group and the ISO/IEC Moving Picture Experts Group. The main goal of the HEVC standardization effort is to enable significantly...

Positive emotions broaden the scope of attention and thought‐action repertoires

The broaden‐and‐build theory (Fredrickson, 199819. Fredrickson , BL . (1998). What good are positive emotions?. Review of General Psychology, 2: 300–319. [CrossRef], [PubMed]View all references, 200121. Fredrickson , BL . (2001). The role of positive...

Estimating the Error Rate of a Prediction Rule: Improvement on Cross-Validation

We construct a prediction rule on the basis of some data, and then wish to estimate the error rate of this rule in classifying future observations. Cross-validation provides a nearly unbiased estimate, using only the original data. Cross-validation turns...

Multiple Comparisons among Means

Methods for constructing simultaneous confidence intervals for all possible linear contrasts among several means of normally distributed variables have been given by Scheffe and Tukey. In this paper the possibility is considered of picking in advance...

Increased survival with enzalutamide in prostate cancer after chemotherapy

P<0.001), the soft-tissue response rate (29% vs. 4%, P<0.001), the quality-of-life response rate (43% vs. 18%, P<0.001), the time to PSA progression (8.3 vs. 3.0 months; hazard ratio,...

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

Summary Background Erlotinib has been shown to improve progression3free survival compared with chemotherapy when given as fi rst3line treatment for Asian patients with non3small3cell lung cancer (NSCLC) with activating EGFR mutations. We aimed to assess...

Robust Tests for the Equality of Variances

Alternative formulations of Levene's test statistic for equality of variances are found to be robust under nonnormality. These statistics use more robust estimators of central location in place of the mean. They are compared with the unmodified Levene's...

Guidelines on the management of valvular heart disease (version 2012)

ACE: angiotensin-converting enzymeAF: atrial fibrillationaPTT: activated partial thromboplastin timeAR: aortic regurgitationARB: angiotensin receptor blockersAS: aortic stenosisAVR: aortic valve replacementBNP: B-type natriuretic peptideBSA:...

Learning and Expectations in Macroeconomics

A crucial challenge for economists is figuring out how people interpret the world and form expectations that will likely influence their economic activity. Inflation, asset prices, exchange rates, investment, and consumption are just some of the economic...

A Theory for Record Linkage

A mathematical model is developed to provide a theoretical framework for a computer-oriented solution to the problem of recognizing those records in two files which represent identical persons, objects or events (said to be matched). A comparison is to...

Acute respiratory distress syndrome: the Berlin Definition.

V. Marco Ranieri, Gordon D. Rubenfeld, B. Taylor Thompson, Niall D. Ferguson, Ellen Caldwell, Eddy Fan, Luigi Camporota, Arthur S. Slutsky, Ards Definition Task Force

Helicopter Parents and Landing Pad Kids: Intense Parental Support of Grown Children

Karen L. Fingerman, Yen-Pi Cheng, Eric D. Wesselmann, Steven H. Zarit, Frank F. Furstenberg, Kira S. Birditt

Regression Analysis of Multivariate Incomplete Failure Time Data by Modeling Marginal Distributions

Many survival studies record the times to two or more distinct failures on each subject. The failures may be events of different natures or may be repetitions of the same kind of event. In this article, we consider the regression analysis of such multivariate...

European position paper on rhinosinusitis and nasal polyps 2012

Wytske J. Fokkens, Valerie J. Lund, Joachim Mullol, Claus Bachert, Isam Alobid, Fuad M. Baroody, Noam A. Cohen, Anders Cervin, Richard Douglas, Philippe Gevaert, Christos Georgalas, Herman Goossens, Richard P. Harvey, Peter W. Hellings, Claire Hopkins, Nick Jones, Guy F. Joos, Livije Kalogjera, Bob Kern, Marek L. Kowalski, David Price, Herbert Riechelmann, Rodney J. Schlosser, Brent A. Senior, Mike Thomas, Elina Toskala, Richard Louis Voegels, De Yun Wang, Peter John Wormald

Molecular Design of Photovoltaic Materials for Polymer Solar Cells: Toward Suitable Electronic Energy Levels and Broad Absorption

Bulk heterojunction (BHJ) polymer solar cells (PSCs) sandwich a blend layer of conjugated polymer donor and fullerene derivative acceptor between a transparent ITO positive electrode and a low work function metal negative electrode. In comparison with...

Youth risk behavior surveillance - United States, 2011.

Steve Kinchen, Shari L. Shanklin, Katherine H. Flint, Joseph Hawkins, William A. Harris, Richard Lowry, Tim McManus, David Chyen, Lisa Whittle, Connie Lim, Howell Wechsler

Bayesian Density Estimation and Inference Using Mixtures

We describe and illustrate Bayesian inference in models for density estimation using mixtures of Dirichlet processes. These models provide natural settings for density estimation and are exemplified by special cases where data are modeled as a sample...

Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease.

Exacerbations occur commonly in patients with moderate or severe chronic obstructive pulmonary disease (COPD) but factors affecting their severity and frequency or effects on quality of life are unknown. We measured daily peak expiratory flow rate (PEFR)...

Goodness of Fit

This Paper defines a class of distribution free measures of goodness of fit; their exact distribution for small samples can be calculated by means of a computer. Two of them have the same asymptotic distribution as the Kolmogorov-Smirnov statistic.

Markov Chain Monte Carlo Convergence Diagnostics: A Comparative Review

A critical issue for users of Markov chain Monte Carlo (MCMC) methods in applications is how to determine when it is safe to stop sampling and use the samples to estimate characteristics of the distribution of interest. Research into methods of computing...

Specification, Estimation, and Evaluation of Smooth Transition Autoregressive Models

This article considers the application of two families of nonlinear autoregressive models, the logistic (LSTAR) and exponential (ESTAR) autoregressive models. This includes the specification of the model based on simple statistical tests: linearity testing...

The Use of Faces to Represent Points in k-Dimensional Space Graphically

A novel method of representing multivariate data is presented. Each point in k-dimensional space, k≤18, is represented by a cartoon of a face whose features, such as length of nose and curvature of mouth, correspond to components of the point. Thus...

Pooled Mean Group Estimation of Dynamic Heterogeneous Panels

It is now quite common to have panels in which both T, the number of time series observations, and N, the number of groups, are quite large and of the same order of magnitude. The usual practice is either to estimate N separate regressions and calculate...

The Influence Curve and its Role in Robust Estimation

This paper treats essentially the first derivative of an estimator viewed as functional and the ways in which it can be used to study local robustness properties. A theory of robust estimation “near” strict parametric models is briefly sketched and...

Life‐Threatening Disparities: The Treatment of Black and White Cancer Patients

Louis A. Penner, Susan Eggly, Jennifer J. Griggs, Willie Underwood, Heather Orom, Terrance L. Albrecht

Marginal Likelihood from the Gibbs Output

In the context of Bayes estimation via Gibbs sampling, with or without data augmentation, a simple approach is developed for computing the marginal density of the sample data (marginal likelihood) given parameter draws from the posterior distribution....

Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy

Strong evidence shows that physical inactivity increases the risk of many adverse health conditions, including major non-communicable diseases such as coronary heart disease, type 2 diabetes, and breast and colon cancers, and shortens life expectancy....

Multiple Comparisons Using Rank Sums

This paper considers the use of rank sums from a combined ranking of k independent samples in order to decide which populations differ. Such a procedure is suggested as a convenient alternative to making separate rankings for each pair of samples, and...

Hadoop: The Definitive Guide

Ready to unlock the power of your data? With this comprehensive guide, youll learn how to build and maintain reliable, scalable, distributed systems with Apache Hadoop. This book is ideal for programmers looking to analyze datasets of any size, and for...

Polymer solar cells

G.P. Li, Yimin Yang

American Thoracic Society/European Respiratory Society Statement on Pulmonary Rehabilitation

Linda Nici, Claudio F. Donner, Richard ZuWallack, Nicolino Ambrosino, Jean Bourbeau, Bartolome Celli, Mariëlle Pkj Engelen, Bonnie Fahy, Chris Garvey, Roger S. Goldstein, Suzanne C. Lareau, Neil MacIntyre, François Maltais, Mike Morgan, Denis E. O'Donnell, Christian Prefault, Jane Reardon, Carolyn L. Rochester, Annemie M. W. J. Schols, Thierry Troosters

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

During the past decade, catheter ablation of atrial fibrillation (AF) has evolved rapidly from an investigational procedure to its current status as a commonly performed ablation procedure in many major hospitals throughout the world. Surgical ablation...

Observation of Electron-Antineutrino Disappearance at Daya Bay

The Daya Bay Reactor Neutrino Experiment has measured a nonzero value for the neutrino mixing angle θ13 with a significance of 5.2 standard deviations. Antineutrinos from six 2.9 GW_(th) reactors were detected in six antineutrino detectors deployed in...

Parameterized Complexity

An approach to complexity theory which offers a means of analysing algorithms in terms of their tractability. The authors consider the problem in terms of parameterized languages and taking "k-slices" of the language, thus introducing readers to new classes...

Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysmography

To study the mechanisms and kinetics underlying the development of increased airway responsiveness (AR) after allergic sensitization, animal models have been invaluable. Using barometric whole-body plethysmography and increases in enhanced pause (Penh)...

Services marketing : integrating customer focus across the firm

This title uniquely focuses on the development of customer relationships through quality service. Reflecting the increasing importance of the service economy, Services Marketing is the only text that put the customer's experience of services at the centre...

Some determinants of social and environmental disclosures in New Zealand companies

Reports the results of a study on the social and environmental disclosure practices of New Zealand companies. In addition to providing an up‐to‐date description of such practices, and placing them in an international context, examines some potential...

A multivariate exponential distribution

plicability. This paper presents some meaningful derivations of a multivariate exponential distribution that serves to indicate conditions under which the distribution is appropriate. Two of these derivations are based on "shock models," and one is based...

Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial

Dabrafenib, an inhibitor of mutated BRAF, has clinical activity with a manageable safety profile in studies of phase 1 and 2 in patients with BRAF V600 -mutated metastatic melanoma. We studied the efficacy of dabrafenib in patients with BRAF V600E...

Comprehensive genomic characterization of squamous cell lung cancers

Peter S. Hammerman, Doug Voet, Michael S. Lawrence, Douglas Voet, Rui Jing, Kristian Cibulskis, Andrey Sivachenko, Petar Stojanov, Aaron McKenna, Eric S. Lander, Stacey Gabriel, Gad Getz, Marcin Imielinski, Elena Helman, Bryan Hernandez, Nam H. Pho, Matthew Meyerson, Andy Chu, Jung E. Hye-Chun, Andrew J. Mungall, Erin Pleasance, A. Gordon Robertson, Payal Sipahimalani, Dominik Stoll, Miruna Balasundaram, Inanc Birol, Yaron S. N. Butterfield, Eric Chuah, Robin Coope, Richard Corbett, Noreen Dhalla, Ranabir Guin, An He, Carrie Hirst, Martin Hirst, Robert A. Holt, Darlene Lee, Haiyan I. Li, Michael Mayo, Richard A. Moore, Karen L. Mungall, Ka Ming Nip, Adam B. Olshen, Jacqueline E. Schein, Jared R. Slobodan, Angela Tam, Nina Thiessen, Richard Varhol, Thomas Zeng, Yongjun Zhao

Markov Chain Sampling Methods for Dirichlet Process Mixture Models

This article reviews Markov chain methods for sampling from the posterior distribution of a Dirichlet process mixture model and presents two new classes of methods. One new approach is to make Metropolis—Hastings updates of the indicators specifying...

Glacial‐interglacial variations in sediment organic carbon accumulation and benthic foraminiferal assemblages on the Bermuda Rise (ODP Site 1063) during MIS 13 to 10

glacial times. Organic d 13 C values are less negative during MIS 12 and MIS 10 than during MIS 11, which is consistent with greater glacial-stage marine productivity. High relative abundances of Oridorsalis umbonatus during glacial intervals probably...

Machine Learning: A Probabilistic Perspective

Today's Web-enabled deluge of electronic data calls for automated methods of data analysis. Machine learning provides these, developing methods that can automatically detect patterns in data and then use the uncovered patterns to predict future data....

Reaching a Consensus

Consider a group of individuals who must act together as a team or committee, and suppose that each individual in the group has his own subjective probability distribution for the unknown value of some parameter. A model is presented which describes how...

Cancer Treatment and Survivorship Statistics, 2012

The number of cancer survivors continues to increase due to the aging and growth of the population and improvements in early detection and treatment. In order for the public health community to better serve these survivors, the American Cancer Society...

Rectangular Confidence Regions for the Means of Multivariate Normal Distributions

For rectangular confidence regions for the mean values of multivariate normal distributions the following conjecture of 0. J. Dunn [3], [4] is proved: Such a confidence region constructed for the case of independent coordinates is, at...

Variations of Box Plots

Box plots display batches of data. Five values from a set of data are conventionally used; the extremes, the upper and lower hinges (quartiles), and the median. Such plots are becoming a widely used tool in exploratory data analysis and in preparing visual...

Ruthenium(II)-catalyzed C-H bond activation and functionalization.

Percia B. Arockiam, Christian Bruneau, Pierre H. Dixneuf

Forecasting Using Principal Components From a Large Number of Predictors

This article considers forecasting a single time series when there are many predictors (N) and time series observations (T). When the data follow an approximate factor model, the predictors can be summarized by a small number of indexes, which we estimate...

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehár, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy, Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Morais Pc, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guoying Yu, Jianjun Yu, Peter Aspesi, Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charlie Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nanxin Li, Jill P. Mesirov, Stacey Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer

Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000.

The authors of this article suggest that information about the distribution of causes of and time trends for child mortality should be periodically updated. They report the latest estimates of causes of child mortality in 2010 with time trends since 2000.

Landscape of transcription in human cells

Eukaryotic cells make many types of primary and processed RNAs that are found either in specific subcellular compartments or throughout the cells. A complete catalogue of these RNAs is not yet available and their characteristic subcellular localizations...

A first course in order statistics

Barry C. Arnold, N. Balakrishnan, H. N. Nagaraja

Cultural Distance Revisited: Towards a More Rigorous Conceptualization and Measurement of Cultural Differences

Cultural distance is a widely used construct in international business, where it has been applied to foreign investment expansion, entry mode choice, and the performance of foreign invested affiliates, among others. The present paper presents a critical...

The Stationary Bootstrap

This article introduces a resampling procedure called the stationary bootstrap as a means of calculating standard errors of estimators and constructing confidence regions for parameters based on weakly dependent stationary observations. Previously, a...

Descriptive translation studies - and beyond

This is an expanded and slightly revised version of the book of the same title which caused quite a stir when it was first published (1995). It thus reflects an additional step in an ongoing research project which was launched in the 1970s. The main objective...

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

401–4. ©2012 AACR. With the rapidly declining cost of next-generation sequencing, and major national and international efforts, including The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) (1), the field of cancer...

Estimation of Error Rates in Discriminant Analysis

Several methods of estimating error rates in Discriminant Analysis are evaluated by sampling methods. Multivariate normal samples are generated on a computer which have various true probabilities of misclassification for different combinations of sample...

Two-Year Outcomes after Transcatheter or Surgical Aortic-Valve Replacement

The rates of death from any cause were similar in the TAVR and surgery groups (hazard ratio with TAVR, 0.90; 95% confidence interval [CI], 0.71 to 1.15; P = 0.41) and at 2 years (Kaplan–Meier analysis)...

Service-dominant logic

Stephen L. Vargo, Robert F. Lusch, Melissa Archpru Akaka, Yi He

International Code of Nomenclature for algae, fungi, and plants (Melbourne Code)

John McNeill, Fred R. Barrie, W.R. Buck, Werner Greuter, D.L. Hawksworth, Patrick S. Herendeen, Sandra Knapp, J. Prado, W.F. Prud'homme van Reine, G.F. Smith, J.H. Wiersema, Nicholas J. Turland

Reporting of Noninferiority and Equivalence Randomized Trials: Extension of the CONSORT 2010 Statement

The CONSORT (Consolidated Standards of Reporting Trials) Statement, which includes a checklist and a flow diagram, is a guideline developed to help authors improve the reporting of the findings from randomized controlled trials. It was updated most recently...

Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study

Methods In our retrospective cohort study , we included patients without previous cancer diagnoses who were fi rst examined with CT in National Health Service (NHS) centres in England, W ales, or Scotland (Great Britain) between 1985 and 2002, when they...

A Statistical View of Some Chemometrics Regression Tools

Chemometrics is a field of chemistry that studies the application of statistical methods to chemical data analysis. In addition to borrowing many techniques from the statistics and engineering literatures, chemometrics itself has given rise to several...

Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

Methods In a cross-sectional study we extracted data on 40 morbidities from a database of 1 751 841 people registered with 314 medical practices in Scotland as of March, 2007. We analysed the data according to the number of morbidities, disorder type...

Microemulsion-based media as novel drug delivery systems

Microemulsions are clear, stable, isotropic mixtures of oil, water and surfactant, frequently in combination with a cosurfactant. These systems are currently of interest to the pharmaceutical scientist because of their considerable potential to act as...

Observation of Reactor Electron Antineutrino Disappearance in the RENO Experiment

: The RENO experiment has observed the disappearance of reactor electron antineutrinos, consistent with neutrino oscillations, with a significance of 4.9 standard deviations. Antineutrinos from six 2.8 GW$_{th}$ reactors at the Yonggwang Nuclear Power...

Sliced Inverse Regression for Dimension Reduction

Modern advances in computing power have greatly widened scientists' scope in gathering and investigating information from many variables, information which might have been ignored in the past. Yet to effectively scan a large pool of variables is not an...

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

The elucidation of breast cancer subgroups and their molecular drivers requires integrated views of the genome and transcriptome from representative numbers of patients. We present an integrated analysis of copy number and gene expression in a discovery...

Structural Complexity II

This is the second volume of a systematic two-volume presentation of the various areas of research in the field of structural complexity. The mathematical theory of computation has developed into a broad and rich discipline within which the theory of...

SLIC Superpixels Compared to State-of-the-Art Superpixel Methods

Computer vision applications have come to rely increasingly on superpixels in recent years, but it is not always clear what constitutes a good superpixel algorithm. In an effort to understand the benefits and drawbacks of existing methods, we empirically...

ChEMBL: a large-scale bioactivity database for drug discovery

Anna Gaulton, Louisa Bellis, A. Patrícia Bento, Jon Chambers, Mark Davies, Anne Hersey, Yvonne Light, Shaun McGlinchey, David Michalovich, Bissan Al-Lazikani, John P. Overington

Research methods in psychology

John J. Shaughnessy, Eugene B. Zechmeister, Jeanne S Zechmeister

Deep Neural Networks for Acoustic Modeling in Speech Recognition: The Shared Views of Four Research Groups

Most current speech recognition systems use hidden Markov models (HMMs) to deal with the temporal variability of speech and Gaussian mixture models (GMMs) to determine how well each state of each HMM fits a frame or a short window of frames of coefficients...

Estimation and Inference in Two-Step Econometric Models

A commonly used procedure in a wide class of impirical applications is to impute unobserved regressors, such as expectations, from an auxiliary econometric model. This two-step (T-S) procedure fails to account for he fact that imputed regessors are measured...

Primer3—new capabilities and interfaces

Polymerase chain reaction (PCR) is a basic molecular biology technique with a multiplicity of uses, including deoxyribonucleic acid cloning and sequencing, functional analysis of genes, diagnosis of diseases, genotyping and discovery of genetic variants....

Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion.

Here, we demonstrate that subject motion produces substantial changes in the timecourses of resting state functional connectivity MRI (rs-fcMRI) data despite compensatory spatial registration and regression of motion estimates from the data. These changes...

Is Daily Mortality Associated Specifically with Fine Particles

Recent epidemiologic studies have consistently reported increased daily mortality associated with exposures to particulate air pollution. Currently, particulate mass is measured as particles smaller than 10 \im (PM10). Fine (PM2 s) and coarse (PM10 -...

On the Exact Variance of Products

A simple exact formula for the variance of the product of two random variables, say, x and y, is given as a function of the means and central product-moments of x and y. The usual approximate variance formula for xy is compared with this exact formula;...

Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis

This comprehensive State of the Art review summarizes the current published knowledge base regarding the pathophysiology and microbiology of pulmonary disease in cystic fibrosis (CF). The molecular basis of CF lung disease including the impact of defective...

Design-adaptive Nonparametric Regression

In this article we study the method of nonparametric regression based on a weighted local linear regression. This method has advantages over other popular kernel methods. Moreover, such a regression procedure has the ability of design adaptation: It adapts...

AMPK: a nutrient and energy sensor that maintains energy homeostasis

D. Grahame Hardie, Fiona A. Ross, Simon A. Hawley

Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2009

Kyu-Won Jung, Sohee Park, Hyun-Joo Kong, Young-Joo Won, Joo Young Lee, Jin-Soo Lee

Geneious Basic

Summary: The two main functions of bioinformatics are the organization and analysis of biological data using computational resources. Geneious Basic has been designed to be an easy-to-use and flexible desktop software application framework for the organization...

Audit and feedback: effects on professional practice and health care outcomes

Noah Ivers, Gro Jamtvedt, Signe Flottorp, Jane M. Young, Jan Odgaard-Jensen, Simon D French, Mary Ann O'Brien, Marit Johansen, Jeremy Grimshaw, Andrew D Oxman

Sentiment Analysis and Opinion Mining

Sentiment analysis and opinion mining is the field of study that analyzes people's opinions, sentiments, evaluations, attitudes, and emotions from written language. It is one of the most active research areas in natural language processing and is also...

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