CiteWeb

WorldWeb citation database

Publications in 2011

Page 1
Data Mining: Concepts and Techniques

The increasing volume of data in modern business and science calls for more complex and sophisticated tools. Although advances in data mining technology have made extensive data collection much easier, it's still always evolving and there is a constant...

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

Comparative analysis of molecular sequence data is essential for reconstructing the evolutionary histories of species and inferring the nature and extent of selective forces shaping the evolution of genes and species. Here, we announce the release of...

Data Mining: Practical Machine Learning Tools and Techniques

Data Mining: Practical Machine Learning Tools and Techniques offers a thorough grounding in machine learning concepts as well as practical advice on applying machine learning tools and techniques in real-world data mining situations. This highly anticipated...

LIBSVM: A library for support vector machines

LIBSVM is a library for Support Vector Machines (SVMs). We have been actively developing this package since the year 2000. The goal is to help users to easily apply SVM to their applications. LIBSVM has gained wide popularity in machine learning and many...

Modern Information Retrieval

Ricardo Baeza-Yates, B. Ribeiro-Neto

Knowledge and Teaching: Foundations of the New Reform

Lee S. Shulman builds his foundation for teaching reform on an idea of teaching that emphasizes comprehension and reasoning, transformation and reflection. "This emphasis is justified," he writes, "by the resoluteness with which research and policy have...

First-price auctions, Dutch auctions, and buy-it-now-prices with Allais paradox bidders

This paper investigates first-price and Dutch auctions when bidders have preferences exhibiting the Allais paradox. We characterize an equilibrium for both auctions, paying particular attention to the dynamic inconsistency problems which can arise with...

Inequalities : theory of majorization and its applications

Albert W. Marshall, Ingram Olkin, Barry C. Arnold

Business research methods

Donald R. Cooper, Pamela S. Schindler

How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions1

The secretion of glucocorticoids (GCs) is a classic endocrine response to stress. Despite that, it remains controversial as to what purpose GCs serve at such times. One view, stretching back to the time of Hans Selye, posits that GCs help mediate the...

Accurate spin-dependent electron liquid correlation energies for local spin density calculations: a critical analysis

the importance of nonand ~~d~~~~~ (4)) and especially the local spin local corrections to the LSDA in atoms, molecules, density approximation (LSDA) to the exchange- and The past several years have seen a very large com'Supported in Part b~ the Natural...

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

The rat estrogen receptor (ER) exists as two subtypes, ERα and ERβ, which differ in the C-terminal ligand binding domain and in the N-terminal transactivation domain. In this study we investigated the messenger RNA expression of both ER subtypes in...

The Biology of Vascular Endothelial Growth Factor

I. Introduction II. Biological Activities of VEGF III. Organization of the VEGF Gene IV. Properties of the VEGF Isoforms V. Regulation of VEGF Gene Expression A. Hypoxia B. Cytokines C. Differentiation and transformation VI. The VEGF Receptors A. Characterization...

The ERA‐Interim reanalysis: configuration and performance of the data assimilation system

ERA-Interim is the latest global atmospheric reanalysis produced by the European Centre for Medium-Range Weather Forecasts (ECMWF). The ERA-Interim project was conducted in part to prepare for a new atmospheric reanalysis to replace ERA-40, which will...

A GUIDE TO THE CHEMICAL CLASSIFICATION OF THE COMMON VOLCANIC ROCKS.

A system is presented whereby volcanic rocks may be classified chemically as follows:I. Subalkaline Rocks:A. Tholeiitic basalt series:Tholeiitic picrite-basalt; tholeiite; tholeiitic andesite.B. Calc-alkali series:High-alumina basalt; andesite; dacite;...

Handbook of the psychology of aging

James E. Birren, K. Warner Schaie, Ronald P. Abeles, Margaret Gatz, Timothy A. Salthouse

Prevention of HIV-1 Infection with Early Antiretroviral Therapy

Background Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. Methods In nine countries, we enrolled 1763 couples in which one partner was HIV-1–positive...

Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β

The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ, which differ in the C-terminal ligand-binding domain and in the N-terminal transactivation domain. In this study, we investigated the estrogenic activity of environmental...

Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.

Methods In a double-blind trial, we randomly assigned 14,264 patients with nonvalvular atrial fibrillation who were at increased risk for stroke to receive either rivaroxaban (at a daily dose of 20 mg) or dose-adjusted warfarin. The per-protocol, as-treated...

FOODBORNE ILLNESS ACQUIRED IN THE UNITED STATES-MAJOR PATHOGENS

Estimates of foodborne illness can be used to direct food safety policy and interventions. We used data from active and passive surveillance and other sources to estimate that each year 31 major pathogens acquired in the United States caused 9.4 million...

THE FEMALE SEXUAL FUNCTION INDEX (FSFI): A MULTIDIMENSIONAL SELF REPORT INSTRUMENT FOR THE ASSESSMENT OF FEMALE SEXUAL FUNCTION

This article presents the development of a brief, self-report measure of female sexual function. Initial face validity testing of questionnaire items, identified by an expert panel, was followed by a study aimed at further refining the questionnaire....

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in...

Principles of distributed database systems

This third edition of a classic textbook can be used to teach at the senior undergraduate and graduate levels. The material concentrates on fundamental theories as well as techniques and algorithms. The advent of the Internet and the World Wide Web, and,...

Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions1

Mitogen-activated protein (MAP) kinases comprise a family of ubiquitous proline-directed, protein-serine/threonine kinases, which participate in signal transduction pathways that control intracellular events including acute responses to hormones and major...

Vascular Endothelial Growth Factor: Basic Science and Clinical Progress

Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and an angiogenic inducer in a variety of in vivo models. Hypoxia has been shown to be a major inducer of VEGF gene transcription. The tyrosine kinases Flt-1 (VEGFR-1)...

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism1

I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA binding properties C. PPAR ligand-binding properties D. Alternative pathways for PPAR activation E. PPAR-mediated transactivation...

Variable Selection via Nonconcave Penalized Likelihood and its Oracle Properties

Variable selection is fundamental to high-dimensional statistical modeling, including nonparametric regression. Many approaches in use are stepwise selection procedures, which can be computationally expensive and ignore stochastic errors in the variable...

Apixaban versus warfarin in patients with atrial fibrillation.

The median duration of follow-up was 1.8 years. The rate of the primary outcome was 1.27% per year in the apixaban group, as compared with 1.60% per year in the war farin group (hazard ratio with apixaban, 0.79; 95% confidence interval...

Unpublished Master's Thesis

Thesis inFo in the eye of the beholder; The effects of Authenticity cues on Purchase intention and overall brand rating, depending on Desire for control han Gie sie, bsc. (0015830)

The Art of Software Testing

The classic, landmark work on software testingThe hardware and software of computing have changed markedly in the three decades since the first edition of The Art of Software Testing, but this book's powerful underlying analysis has stood the test of...

A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum

The free and nonspecifically bound plasma hormone levels generally reflect the clinical situation more accurately than total plasma hormone levels. Hence, it is important to have reliable indexes of these fractions. The apparent free testosterone (T)...

Amazon's Mechanical Turk: A New Source of Inexpensive, Yet High-Quality, Data?

Amazon's Mechanical Turk (MTurk) is a relatively new website that contains the major elements required to conduct research: an integrated participant compensation system; a large participant pool; and a streamlined process of study design, participant...

ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elev

ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation : The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation...

Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline

Objective: The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency. Participants: The Task Force was composed of...

Distributed Optimization and Statistical Learning via the Alternating Direction Method of Multipliers

Many problems of recent interest in statistics and machine learning can be posed in the framework of convex optimization. Due to the explosion in size and complexity of modern datasets, it is increasingly important to be able to solve problems with a...

Density Functional Theory

R.M. Dreizler, Eberhard Engel

Full-length transcriptome assembly from RNA-Seq data without a reference genome

Massively parallel sequencing of cDNA has enabled deep and efficient probing of transcriptomes. Current approaches for transcript reconstruction from such data often rely on aligning reads to a ref ...

Chemical reactor analysis and design

Gilbert F. Froment, Kenneth B. Bischoff, Juray De Wilde

Adiponectin and Adiponectin Receptors

Metabolic syndrome is thought to result from obesity and obesity-linked insulin resistance. Obesity in adulthood is characterized by adipocyte hypertrophy. Adipose tissue participates in the regulation of energy homeostasis as an important endocrine organ...

Modern quantum mechanics

純 桜井, 三孚 段

Tools and Resources

Summary:Data processing, analysis and visualization (datPAV) is an exploratory tool that allows experimentalist to quickly assess the general characteristics of the data. This platform-independent software is designed as a generic tool to process and...

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

The National Institute on Aging and the Alzheimer’s Association charged a workgroup with the task of revising the 1984 criteria for Alzheimer’s disease (AD) dementia. The workgroup sought to ensure that the revised criteria would be flexible enough...

Reversibility and Stochastic Networks

This classic in stochastic network modelling broke new ground when it was published in 1979, and it remains a superb introduction to reversibility and its applications. The book concerns behaviour in equilibrium of vector stochastic processes or stochastic...

Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans

Insulin resistance plays an important role in the pathophysiology of diabetes and is associated with obesity and other cardiovascular risk factors. The “gold standard” glucose clamp and minimal model analysis are two established methods for determining...

Cultivating Competence, Self-Efficacy, and Intrinsic Interest Through Proximal Self-Motivation

The present experiment tested the hypothesis that self-motivation through proximal goal setting serves as an effective mechanism for cultivating competencies, self-percepts of efficacy, and intrinsic interest. Children who exhibited gross deficits and...

Real-time human pose recognition in parts from single depth images

We propose a new method to quickly and accurately predict 3D positions of body joints from a single depth image, using no temporal information. We take an object recognition approach, designing an intermediate body parts representation that maps the difficult...

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

Background Ipilimumab monotherapy (at a dose of 3 mg per kilogram of body weight), as compared with glycoprotein 100, improved overall survival in a phase 3 study involving patients with previously treated metastatic melanoma. We conducted a phase 3 study...

Subcutaneous and Visceral Adipose Tissue: Their Relation to the Metabolic Syndrome

Methods for assessment, e.g., anthropometric indicators and imaging techniques, of several phenotypes of human obesity, with special reference to abdominal fat content, have been evaluated. The correlation of fat distribution with age, gender, total body...

Scikit-learn: Machine Learning in Python

Scikit-learn is a Python module integrating a wide range of state-of-the-art machine learning algorithms for medium-scale supervised and unsupervised problems. This package focuses on bringing machine learning to non-specialists using a general-purpose...

ESC/EAS Guidelines for the management of dyslipidaemias: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)

European Association for Cardiovascular Prevention & Rehabilitation Reiner, Zeljko Catapano, Alberico L De Backer, Guy Graham, Ian Taskinen, Marja-Riitta Wiklund, Olov Agewall, Stefan Alegria, Eduardo Chapman, M John Durrington, Paul Erdine, Serap Halcox,...

Ghrelin Enhances Appetite and Increases Food Intake in Humans

Ghrelin is a recently identified endogenous ligand for the growth hormone secretagogue receptor. It is synthesized predominantly in the stomach and found in the circulation of healthy humans. Ghrelin has been shown to promote increased food intake, weight...

The SPIN Model Checker: Primer and Reference Manual

The SPIN Model Checker is used for both teaching software verification techniques, and for validating large scale applications. The growing number of users has created a need for a more comprehensive user guide and a standard reference manual that describes...

Happiness : lessons from a new science

In this new edition of his landmark book, Richard Layard shows that there is a paradox at the heart of our lives. Most people want more income. Yet as societies become richer, they do not become happier. This is not just anecdotally true, it is the story...

Motivation and Education: The Self-Determination Perspective

Self-determination theory (Deci & Ryan, 1985, 1991), when applied to the realm of education, is concerned primarily with promoting in students an interest in learning, a valuing of education, and a confidence in their own capacities and attributes. These...

Global quantification of mammalian gene expression control

Gene expression is a multistep process that involves the transcription, translation and turnover of messenger RNAs and proteins. Although it is one of the most fundamental processes of life, the entire cascade has never been quantified on a genome-wide...

Abiraterone and increased survival in metastatic prostate cancer

Background: Biosynthesis of extragonadal androgen may contribute to the progression of castration-resistant prostate cancer. We evaluated whether abiraterone acetate, an inhibitor of androgen biosynthesis, prolongs overall survival among patients with...

Boceprevir for untreated chronic HCV genotype 1 infection

Background Peginterferon–ribavirin therapy is the current standard of care for chronic infection with hepatitis C virus (HCV). The rate of sustained virologic response has been below 50% in cases of HCV genotype 1 infection. Boceprevir, a potent oral...

Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis1

I. Introduction A. Background and historical perspective B. Definition of PCOS II. Insulin Action in PCOS A. Glucose tolerance B. Insulin action in vivo in PCOS C. Insulin secretion in PCOS D. Insulin clearance in PCOS E. Cellular and molecular mechanisms...

mTOR: from growth signal integration to cancer, diabetes and ageing

Roberto Zoncu, Alejo Efeyan, David M. Sabatini

ESC Guidelines for the Management of Acute Coronary Syndromes in Patients Presenting Without Persistent ST-Segment Elevation

ABOARD: Angioplasty to Blunt the Rise of Troponin in Acute Coronary Syndromes Randomized for an Immediate or Delayed InterventionACC: American College of CardiologyACE: angiotensin-converting enzymeACS: acute coronary syndromesACT: activated...

2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Intervention

Glenn N. Levine, Eric R. Bates, James C. Blankenship, Steven R. Bailey, John A. Bittl, Bojan Cercek, Charles E. Chambers, Stephen G. Ellis, Robert A. Guyton, Umesh N. Khot, Richard A. Lange, Laura Mauri, Roxana Mehran, Issam Moussa, Debabrata Mukherjee, Brahmajee K. Nallamothu, Henry H. Ting

Self-rated health: a predictor of mortality among the elderly.

Data from the Manitoba Longitudinal Study on Aging are used to test the hypothesis that self-rated health status is a good predictor of mortality among the elderly. The data are for 3128 elderly noninstitutionalized residents of Manitoba Canada who were...

Obesity and overweight

The World Health Organization (WHO) defines obesity and overweight as excessive fat accumulation that presents a health risk. Body mass index (BMI) is used in the classification of patients as underweight, normal weight, overweight or obese (see Table...

Semantic web services

Carlos Pedrinaci, John Domingue, Amit P. Sheth

Interventions for preventing obesity in children

Childhood obesity can cause social, psychological and health problems, and is linked to obesity later in life and poor health outcomes as an adult. Obesity development is related to physical activity and nutrition. To prevent obesity, 55 studies conducted...

Algorithms for the Reduction of the Number of Points Required to Represent a Digitized Line or its Caricature

All digitizing methods, as a general rule, record lines with far more data than is necessary for accurate graphic reproduction or for computer analysis. Two algorithms to reduce the number of points required to represent the line and, if desired, produce...

Motivating project-based learning: Sustaining the doing, supporting the learning

Project-based learning is a comprehensive approach to classroom teaching and learning that is designed to engage students in investigation of authentic problems. In this article, we present an argument for why projects have the potential to help people...

Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

I. Introduction II. Role of Osteoblasts/Stromal Cells in Osteoclast Differentiation and Function A. Origin of osteoclasts B. Stimulation of osteoclast differentiation by osteoblasts/stromal cells C. Stimulation of osteoclast function by osteoblasts/stromal...

Model-Based Clustering, Discriminant Analysis, and Density Estimation

Cluster analysis is the automated search for groups of related observations in a dataset. Most clustering done in practice is based largely on heuristic but intuitively reasonable procedures, and most clustering methods available in commercial software...

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis1

The adult skeleton regenerates by temporary cellular structures that comprise teams of juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A considerable body of evidence accumulated during the last decade has shown that...

Introduction to Autonomous Mobile Robots

Mobile robots range from the Mars Pathfinder mission's teleoperated Sojourner to the cleaning robots in the Paris Metro. This text offers students and other interested readers an introduction to the fundamentals of mobile robotics, spanning the mechanical,...

Evaluating the public health impact of health promotion interventions: the RE-AIM framework.

This paper proposes the RE-AIM model for evaluating public health interventions that assesses five dimensions namely reach efficacy adoption implementation and maintenance. These dimensions occur at multiple levels such as the organizational or community...

UCHIME improves sensitivity and speed of chimera detection

Motivation: Chimeric DNA sequences often form during polymerase chain reaction amplification, especially when sequencing single regions (e.g. 16S rRNA or fungal Internal Transcribed Spacer) to assess diversity or compare populations. Undetected chimeras...

Optimization of Gaussian-type basis sets for local spin density functional calculations. Part I. Boron through neon, optimization technique and validation

Gaussian-type orbital and auxiliary basis sets have been optimized for local spin density functional calculations. This first paper deals with the atoms boron through neon. Subsequent papers will provide a list through xenon. The basis sets have been...

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

mean BMI worldwide increased by 0.4 kg/m 2 per decade (95% uncertainty interval 0.2– 0.6, posterior probability of being a true increase 0.999) for men and 0.5 kg/m...

The study of transnationalism: pitfalls and promise of an emergent research field

This introductory article defines the concept of transnationalism, provides a typology of this heterogeneous set of activities, and reviews some of the pitfalls in establishing and validating the topic as a novel research field. A set of guidelines to...

Brain Corticosteroid Receptor Balance in Health and Disease1

I. Introduction II. Corticosteroid Receptor Properties A. Corticosteroid receptor diversity in brain and pituitary B. Access of corticosteroids to brain receptors C. Expression of MR, GR, and receptor variants D. Regulation of transcriptional activity...

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.

This new classification strategy is based on a multidisciplinary approach to diagnosis of lung adenocarcinoma that incorporates clinical, molecular, radiologic, and surgical issues, but it is primarily based on histology. This classification is intended...

The Silenced Dialogue: Power and Pedagogy in Educating Other People's Children

Lisa Delpit uses the debate over process-oriented versus skills-oriented writing instruction as the starting-off point to examine the "culture of power" that exists in society in general and in the educational environment in particular. She analyzes five...

Medium and techniques for induction and growth of monocotyledonous and dicotyledonous plant cell cultures

The composition of a medium is described that proved useful to culture callus of a variety of monocotyledonous and dicotyledonous plants. Growth on the medium was often better than on some other excellent media. In addition to supporting rapid cell growth,...

From game design elements to gamefulness: defining "gamification"

Recent years have seen a rapid proliferation of mass-market consumer software that takes inspiration from video games. Usually summarized as "gamification", this trend connects to a sizeable body of existing concepts and research in human-computer interaction...

Guidelines for the Prevention of Intravascular Catheter-related Infections

These guidelines have been developed for practitioners who insert catheters and for persons responsible for surveillance and control of infections in hospital, outpatient, and home health-care settings. This report was prepared by a working group comprising...

The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials

Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and...

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

The pathophysiological process of Alzheimer’s disease (AD) is thought to begin many years before the diagnosis of AD dementia. This long “preclinical” phase of AD would provide a critical opportunity for therapeutic intervention; however, we need...

Clinical gynecologic endocrinology and infertility

Leon Speroff, Robert H. Glass, Nathan Kase

Assessment of Biotic Integrity Using Fish Communities

Man's activities have had profound, and usually negative, influences on freshwater fishes from the smallest streams to the largest rivers. Some negative effects are due to contaminants, while others are associated with changes in watershed hydrology,...

ENSEMBLE EMPIRICAL MODE DECOMPOSITION: A NOISE-ASSISTED DATA ANALYSIS METHOD

A new Ensemble Empirical Mode Decomposition (EEMD) is presented. This new approach consists of sifting an ensemble of white noise-added signal (data) and treats the mean as the final true result. Finite, not infinitesimal, amplitude white noise is necessary...

Policies That Support Professional Development In an Era of Reform

Linda Darling-Hammond, Milbrey Wallin McLaughlin

YET ANOTHER CHAOTIC ATTRACTOR

This Letter reports the finding of a new chaotic at tractor in a simple three-dimensional autonomous system, which resembles some familiar features from both the Lorenz and Rossler at tractors.

Cytoscape 2.8: new features for data integration and network visualization

Michael Smoot, Keiichiro Ono, Johannes Ruscheinski, Peng-Liang Wang, Trey Ideker

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

Summary Background Data for trends in glycaemia and diabetes prevalence are needed to understand the effects of diet and lifestyle within populations, assess the performance of interventions, and plan health services. No consistent and comparable global...

Integrated genomic analyses of ovarian carcinoma

Daphne W. Bell, Andrew Berchuck, Michael J. Birrer, Jeremy Chien, Daniel W. Cramer, Fanny Dao, Rajiv Dhir, Phillip DiSaia, H. Gabra, P. Glenn, Andrew K. Godwin, Jenny Gross, Lynn C. Hartmann, Ming-Shyan Huang, David Huntsman, Mary Iacocca, Marcin Imielinski, Steve E. Kalloger, Beth Y. Karlan, Douglas A. Levine, Gordon B. Mills, Carl Morrison, David G. Mutch, Narciso Olvera, Sandra Orsulic, Karen Park, Nicholas Petrelli, Brenda Rabeno, Janet S. Rader, Sikic Bi, Karen Smith-McCune, Anil K. Sood, David Bowtell, Robert Penny, Joseph R. Testa, Kai-Hsin Chang, Huyen Dinh, Jennifer Drummond, Gerald R. Fowler, Preethi H. Gunaratne, Alicia Hawes, Christie Kovar, Lora Lewis, Margaret Morgan, Irene Newsham, Jireh Santibanez, Jeffrey G. Reid, Lisa R. Treviño, Ye Wu, Meng C. Wang

Trinity: reconstructing a full-length transcriptome without a genome from RNA-Seq data

Manfred Grabherr, Brian J. Haas, Moran Yassour, Joshua Z. Levin, Dawn Anne Thompson, Ido Amit, Xian Adiconis, Lin Fan, Raktima Raychowdhury, Qiandong Zeng, Zehua Chen, Evan Mauceli, Nir Hacohen, Andreas Gnirke, Nicholas Rhind, Federica Di Palma, Bruce W. Birren, Chad Nusbaum, Kerstin Lindblad-Toh, Nir Friedman, Aviv Regev

Increasing Solar Absorption for Photocatalysis with Black Hydrogenated Titanium Dioxide Nanocrystals

When used as a photocatalyst, titanium dioxide (TiO2) absorbs only ultraviolet light, and several approaches, including the use of dopants such as nitrogen, have been taken to narrow the band gap of TiO2. We demonstrated a conceptually different approach...

Nuclear Receptor Coregulators: Cellular and Molecular Biology1

I. Introduction A. The nuclear receptor superfamily B. General transcription factors (GTFs) II. Nuclear Receptor Coactivators A. Background B. Receptor-associated proteins and coactivators III. Nuclear Receptor Corepressors A. Background B. Corepressors...

Effect of the damping function in dispersion corrected density functional theory

It is shown by an extensive benchmark on molecular energy data that the mathematical form of the damping function in DFT-D methods has only a minor impact on the quality of the results. For 12 different functionals, a standard "zero-damping" formula and...

Robust principal component analysis

This article is about a curious phenomenon. Suppose we have a data matrix, which is the superposition of a low-rank component and a sparse component. Can we recover each component individuallyq We prove that under some suitable assumptions, it is possible...

Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes

In both type 1 and type 2 diabetes, the late diabetic complications in nerve, vascular endothelium, and kidney arise from chronic elevations of glucose and possibly other metabolites including free fatty acids (FFA). Recent evidence suggests that common...

Self-Efficacy and Academic Motivation

Academic motivation is discussed in terms of self-efficacy, an individual's judgments of his or her capabilities to perform given actions. After presenting an overview of self-efficacy theory, I contrast self-efficacy with related constructs (perceived...

Sex Steroids and the Construction and Conservation of the Adult Skeleton

Here we review and extend a new unitary model for the pathophysiology of involutional osteoporosis that identifies estrogen (E) as the key hormone for maintaining bone mass and E deficiency as the major cause of age-related bone loss in both sexes. Also,...

Cytoscape 2.8

Summary: Cytoscape is a popular bioinformatics package for biological network visualization and data integration. Version 2.8 introduces two powerful new features—Custom Node Graphics and Attribute Equations—which can be used jointly to greatly enhance...

Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications

Vitamin D deficiency is common in the elderly, especially in the housebound and in geriatric patients. The establishment of strict diagnostic criteria is hampered by differences in assay methods for 25-hydroxyvitamin D. The synthesis of vitamin D3 in...

Fundamentals of engineering thermodynamics

Michael J. Moran, Howard N. Shapiro

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study

Summary Background Activating mutations in EGFR are important markers of response to tyrosine kinase inhibitor (TKI) therapy in non-small-cell lung cancer (NSCLC). The OPTIMAL study compared effi cacy and tolerability of the TKI erlotinib versus standard...

Semantic Similarity in a Taxonomy: An Information-Based Measure and its Application to Problems of Ambiguity in Natural Language

: This article presents a measure of semantic similarity in an IS-A taxonomy based on the notion of shared information content. Experimental evaluation against a benchmark set of human similarity judgments demonstrates that the measure performs better...

Axillary Dissection vs No Axillary Dissection in Women With Invasive Breast Cancer and Sentinel Node Metastasis: A Randomized Clinical Trial

Context Sentinel lymph node dissection (SLND) accurately identifies nodal metastasis of early breast cancer, but it is not clear whether further nodal dissection affects survival.Objective To determine the effects of complete axillary lymph node dissection...

Cellular Actions of the Insulin-Like Growth Factor Binding Proteins

In addition to their roles in IGF transport, the six IGF-binding proteins (IGFBPs) regulate cell activity in various ways. By sequestering IGFs away from the type I IGF receptor, they may inhibit mitogenesis, differentiation, survival, and other IGF-stimulated...

Fundamentals of WiMAX: Understanding Broadband Wireless Networking

This is the eBook version of the printed book. Praise for Fundamentals of WiMAX "This book is one of the most comprehensive books I have reviewed ... it is a must-read for engineers and students planning to remain current or who plan to pursue a career...

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that play a central role in host cell recognition and responses to microbial pathogens. TLR-mediated recognition of components derived from a wide range of pathogens...

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