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Protein measurement with the folin phenol reagent

Oliver H. Lowry, Nira J. Rosebrough, A. Lewis Farr, Rose J. Randall

Molecular cloning : a laboratory manual

Sambrook J, Edward F. Fritsch, Tom Maniatis

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

A protein determination method which involves the binding of Coomassie Brilliant Blue G-250 to protein is described. The binding of the dye to protein causes a shift in the absorption maximum of the dye from 465 to 595 nm, and it is the increase in absorption...

Density‐functional thermochemistry. III. The role of exact exchange

Despite the remarkable thermochemical accuracy of Kohn–Sham density‐functional theories with gradient corrections for exchange‐correlation [see, for example, A. D. Becke, J. Chem. Phys. 96, 2155 (1992)], we believe that further improvements are...

The Moderator-Mediator Variable Distinction in Social Psychological Research: Conceptual, Strategic, and Statistical Considerations

In this article, we attempt to distinguish between the properties of moderator and mediator variables at a number of levels. First, we seek to make theorists and researchers aware of the importance of not using the terms moderator and mediator interchangeably...

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

The BLAST programs are widely used tools for searching protein and DNA databases for sequence similarities. For protein comparisons, a variety of definitional, algorithmic and statistical refinements described here permits the execution time of the BLAST...

A short history of SHELX

An account is given of the development of the SHELX system of computer programs from SHELX-76 to the present day. In addition to identifying useful innovations that have come into general use through their implementation in SHELX, a critical analysis...

Generalized Gradient Approximation Made Simple

Generalized gradient approximations (GGA’s) for the exchange-correlation energy improve upon the local spin density (LSD) description of atoms, molecules, and solids. We present a simple derivation of a simple GGA, in which all parameters (other than...

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

The two most commonly used methods to analyze data from real-time, quantitative PCR experiments are absolute quantification and relative quantification. Absolute quantification determines the input copy number, usually by relating the PCR signal to a...

Firm Resources and Sustained Competitive Advantage

Understanding sources of sustained competitive advantage has be­ come a major area of research in strategic management. Building on the assumptions that strategic resources are heterogeneously distrib­ uted across firms and that these differences are...

Maximum likelihood from incomplete data via the EM algorithm

A. P. Dempster, Nan M. Laird, Donald B. Rubin

Nonparametric Estimation from Incomplete Observations

In lifetesting, medical follow-up, and other fields the observation of the time of occurrence of the event of interest (called a death) may be prevented for some of the items of the sample by the previous occurrence of some other event (called a loss)....

The presentation of self in everyday life

hen an individual enters the presence of oth ers, they commonly seek to acquire information about him or to bring into play information about him already possessed. They will be interested in his general socio-economic status, his concep tion of self,...

Distinction : a social critique of the judgement of taste

We publish here the main part of Bourdieu text, which comprises of the fragments of his famous book “Distinction: A Social Critique of the Judgement of Taste” (D. Gruski is responsible for the pages for choice).

PROSPECT THEORY: AN ANALYSIS OF DECISION UNDER RISK

This paper presents a critique of expected utility theory as a descriptive model of decision making under risk, and develops an alternative model, called prospect theory. Choices among risky prospects exhibit several pervasive effects that are inconsistent...

A RATING SCALE FOR DEPRESSION

Full textFull text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. 56575859606162

THE ASSESSMENT AND ANALYSIS OF HANDEDNESS: THE EDINBURGH INVENTORY

The need for a simply applied quantitative assessment of handedness is discussed and some previous forms reviewed. An inventory of 20 items with a set of instructions and response- and computational-conventions is proposed and the results obtained from...

Probabilistic Reasoning in Intelligent Systems: Networks of Plausible Inference

From the Publisher:Probabilistic Reasoning in Intelligent Systems is a complete andaccessible account of the theoretical foundations and computational methods that underlie plausible reasoning under uncertainty. The author provides a coherent explication...

Particle swarm optimization

A concept for the optimization of nonlinear functions using particle swarm methodology is introduced. The evolution of several paradigms is outlined, and an implementation of one of the paradigms is discussed. Benchmark testing of the paradigm is described,...

Current protocols in molecular biology

R E Kingston, David D. Moore, J. L. Smith

Distinctive Image Features from Scale-Invariant Keypoints

This paper presents a method for extracting distinctive invariant features from images that can be used to perform reliable matching between different views of an object or scene. The features are invariant to image scale and rotation, and are shown to...

A new look at the statistical model identification

The history of the development of statistical hypothesis testing in time series analysis is reviewed briefly and it is pointed out that the hypothesis testing procedure is not adequately defined as the procedure for statistical model identification. The...

The Theory of Planned Behavior

Research dealing with various aspects of* the theory of planned behavior (Ajzen, 1985, 1987) is reviewed, and some unresolved issues are discussed. In broad terms, the theory is found to be well supported by empirical evidence. Intentions to perform behaviors...

The Strength of Weak Ties

Analysis of social networks is suggested as a tool for linking micro and macro levels of sociological theory. The procedure is illustrated by elaboration of the macro implications of one aspect of small-scale interaction: the strength of dyadic ties....

Regression Models and Life-Tables

The analysis of censored failure times is considered. It is assumed that on each individual are available values of one or more explanatory variables. The hazard function (age-specific failure rate) is taken to be a function of the explanatory variables...

Numerical recipes: the art of scientific computing

Brian P. Flannery, Saul A. Teukolsky, William T. Vetterling

Applied logistic regression

From the reviews of the First Edition. "An interesting, useful, and well-written book on logistic regression models... Hosmer and Lemeshow have used very little mathematics, have presented difficult concepts heuristically and through illustrative examples,...

Principles of optics

Max Born, Emil Wolf

The CLUSTAL_X Windows Interface: Flexible Strategies for Multiple Sequence Alignment Aided by Quality Analysis Tools

CLUSTAL X is a new windows interface for the widely-used progressive multiple sequence alignment program CLUSTAL W. The new system is easy to use, providing an integrated system for performing multiple sequence and profile alignments and analysing the...

Making Democracy Work: Civic Traditions In Modern Italy

Robert D. Putnam, Robert D. Putnam, Raffaella Y. Nanetti

The Hospital Anxiety and Depression Scale

A self-assessment scale has been developed and found to be a reliable instrument for detecting states of depression and anxi­ ety in the setting of an hospital medical outpatient clinic. The anxiety and depressive subscales are also valid measures of...

Social Capital in the Creation of Human Capital

In this paper, the concept of social capital is introduced and illustrated, its forms are described, the social structural conditions under which it arises are examined, and it is used in an analysis ol dropouts from high school. Use of the concept of...

Elements of information theory

Thomas M. Cover, Joy A. Thomas

Principles and procedures of statistics.

R. G. D. Steel, J. H. Torrie

Controlling the False Discovery Rate: a Practical and Powerful Approach to Multiple Testing

SUMMARY The common approach to the multiplicity problem calls for controlling the familywise error rate (FWER). This approach, though, has faults, and we point out a few. A different approach to problems of multiple significance testing is presented....

Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives

This article examines the adequacy of the “rules of thumb” conventional cutoff criteria and several new alternatives for various fit indexes used to evaluate model fit in practice. Using a 2‐index presentation strategy, which includes using the...

Matrix analysis

Linear algebra and matrix theory are fundamental tools in mathematical and physical science, as well as fertile fields for research. This new edition of the acclaimed text presents results of both classic and recent matrix analyses using canonical forms...

Economic Action and Social Structure: The Problem of Embeddedness

How behavior and institutions are affected by social relations is one of the classic questions of social theory. This paper concerns the extent to which economic action is embedded in structures of social relations, in modern industrial society. Although...

Data Mining: Concepts and Techniques

The increasing volume of data in modern business and science calls for more complex and sophisticated tools. Although advances in data mining technology have made extensive data collection much easier, it's still always evolving and there is a constant...

An evolutionary theory of economic change

Sidney G. Winter, Richard R. Nelson

Multiple regression: testing and interpreting interactions

Leona S. Aiken, Stephen G. West, Raymond R. Reno

The evolution of cooperation

Cooperation in organisms, whether bacteria or primates, has been a difficulty for evolutionary theory since Darwin. On the assumption that interactions between pairs of individuals occur on a probabilistic basis, a model is developed based on the concept...

The Pricing of Options and Corporate Liabilities

If options are correctly priced in the market, it should not be possible to make sure profits by creating portfolios of long and short positions in options and their underlying stocks. Using this principle, a theoretical valuation formula for options...

Building Theories from Case Study Research

This paper describes the process of inducting theory using case studies-from specifying the research questions to reaching closure. Some features of the process, such as problem definition and construct validation, are similar to hypothesis-testing research....

Random sample consensus: a paradigm for model fitting with applications to image analysis and automated cartography

A new paradigm, Random Sample Consensus (RANSAC), for fitting a model to experimental data is introduced. RANSAC is capable of interpreting/smoothing data containing a significant percentage of gross errors, and is thus ideally suited for applications...

Multiple regression: testing and interpreting interactions

Leona S. Aiken, Stephen G. West, Raymond R. Reno

Equation of State Calculations by Fast Computing Machines

A general method, suitable for fast computing machines, for investigating such properties as equations of state for substances consisting of interacting individual molecules is described. The method consists of a modified Monte Carlo integration over...

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

Comparative analysis of molecular sequence data is essential for reconstructing the evolutionary histories of species and inferring the nature and extent of selective forces shaping the evolution of genes and species. Here, we announce the release of...

Perceived usefulness, perceived ease of use, and user acceptance of information technology

Valid measurement scales for predicting user acceptance of computers are in short supply. Most subjective measures used in practice are unvalidated, and their relationship to system usage is unknown. The present research develops and validates new scales...

Gaussian basis sets for use in correlated molecular calculations. I. The atoms boron through neon and hydrogen

In the past, basis sets for use in correlated molecular calculations have largely been taken from single configuration calculations. Recently, Almlof, Taylor, and co‐workers have found that basis sets of natural orbitals derived from correlated atomic...

Statistical Learning Theory

Yuhai Wu, Vladimir Vapnik

Data Mining: Practical Machine Learning Tools and Techniques

Data Mining: Practical Machine Learning Tools and Techniques offers a thorough grounding in machine learning concepts as well as practical advice on applying machine learning tools and techniques in real-world data mining situations. This highly anticipated...

Convex Optimization

Boyd, Vandenberghe, Faybusovich

Econometric Analysis of Cross Section and Panel Data

This graduate text provides an intuitive but rigorous treatment of contemporary methods used in microeconometric research. The book makes clear that applied microeconometrics is about the estimation of marginal and treatment effects, and that parametric...

Sample Selection Bias as a Specification Error

Sample selection bias as a specification error This paper discusses the bias that results from using non-randomly selected samples to estimate behavioral relationships as an ordinary specification error or «omitted variables» bias. A simple consistent...

LIBSVM: A library for support vector machines

LIBSVM is a library for Support Vector Machines (SVMs). We have been actively developing this package since the year 2000. The goal is to help users to easily apply SVM to their applications. LIBSVM has gained wide popularity in machine learning and many...

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

A technique for conveniently radiolabeling DNA restriction endonuclease fragments to high specific activity is described. DNA fragments are purified from agarose gels directly by ethanol precipitation and are then denatured and labeled with the large...

Law and Finance

This paper examines legal rules covering protection of corporate shareholders and creditors, the origin of these rules, and the quality of their enforcement in 49 countries. The results show that common†law countries generally have the strongest,...

Clinical diagnosis of Alzheimer's disease Report of the NINCDS‐ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

Alzheimer’s disease is a brain disorder characterized by a progressive dementia that occurs in middle or late life. The pathologic characteristics are degeneration of specific nerve cells, presence of neuritic plaques, and neurofibrillary tangles. Alterations...

Processing of X-ray diffraction data collected in oscillation mode

X-ray data can be collected with zero-, one-, and two-dimensional detectors, zero-dimensional (single counter) being the simplest and two-dimensional the most efficient in terms of measuring diffracted X-rays in all directions. To analyze the single-crystal...

A power primer.

One possible reason for the continued neglect of statistical power analysis in research in the behavioral sciences is the inaccessibility of or difficulty with the standard material. A convenient, although not comprehensive, presentation of required sample...

A tutorial on hidden Markov models and selected applications in speech recognition

This tutorial provides an overview of the basic theory of hidden Markov models (HMMs) as originated by L.E. Baum and T. Petrie (1966) and gives practical details on methods of implementation of the theory along with a description of selected applications...

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

SummarySome simple formulae were obtained which enable us to estimate evolutionary distances in terms of the number of nucleotide substitutions (and, also, the evolutionary rates when the divergence times are known). In comparing a pair of nucleotide...

Neural Networks for Pattern Recognition

From the Publisher:This is the first comprehensive treatment of feed-forward neural networks from the perspective of statistical pattern recognition. After introducing the basic concepts, the book examines techniques for modelling probability density...

Applied regression analysis

Norman R. Draper, Harry Smith

Design Patterns: Elements of Reusable Object-Oriented Software

The book is an introduction to the idea of design patterns in software engineering, and a catalog of twenty-three common patterns. The nice thing is, most experienced OOP designers will find out they've known about patterns all along. It's just that they've...

Conduction of heat in solids

H. S. (Horatio Scott) Carslaw, J. C. Jaeger

Structural Equation Modeling in Practice: A Review and Recommended Two-Step Approach

In this article, we provide guidance for substantive researchers on the use of structural equation modeling in practice for theory testing and development. We present a comprehensive, two-step modeling approach that employs a series of nested models and...

Dynamic Capabilities and Strategic Management

The dynamic capabilities framework analyzes the sources and methods of wealth creation and capture by private enterprise firms operating in environments of rapid technological change. The competitive advantage of firms is seen as resting on distinctive...

Development as Freedom

In Development as Freedom Amartya Sen explains how in a world of unprecedented increase in overall opulence millions of people living in the Third World are still unfree. Even if they are not technically slaves, they are denied elementary freedoms and...

How to do things with words

J. L. (John Langshaw) Austin, J. O. Urmson, Marina Sbisà

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