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CiteWeb id: 20140001071

CiteWeb score: 228

DOI: 10.1016/j.bbagrm.2014.03.001

article i nfo A major mechanism regulating the accessibility and function of eukaryotic genomes are the covalent modifications to DNA and histone proteins that dependably package our genetic information inside the nucleus of every cell. Formally postulated over a decade ago, it is becoming increasingly clear that post- translational modifications (PTMs) on histones act singly and in combination to form a language or 'code' that is read by specialized proteins to facilitate downstream functions in chromatin. Underappreciated at the time wasthelevelofcomplexityharboredbothwithinhistonePTMsandtheircombinations,aswellaswithinthepro-

The publication "Interpreting the language of histone and DNA modifications" is placed in the Top 10000 in 2014.
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