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CiteWeb id: 20130000040

CiteWeb score: 2643

DOI: 10.1126/science.1232033

Clustered regularly interspaced short palindromic repeats (CRISPR) function as part of an adaptive immune system in a range of prokaryotes: Invading phage and plasmid DNA is targeted for cleavage by complementary CRISPR RNAs (crRNAs) bound to a CRISPR-associated endonuclease (see the Perspective by [ van der Oost ][1]). Cong et al. (p. [819][2], published online 3 January) and Mali et al. (p. [823][3], published online 3 January) adapted this defense system to function as a genome editing tool in eukaryotic cells. [1]: /lookup/doi/10.1126/science.1234726 [2]: /lookup/doi/10.1126/science.1231143 [3]: /lookup/doi/10.1126/science.1232033

The publication "RNA-Guided Human Genome Engineering via Cas9" is placed in the Top 10000 of the best publications in CiteWeb. Also in the category Biology it is included to the Top 10000. Additionally, the publicaiton "RNA-Guided Human Genome Engineering via Cas9" is placed in the Top 100 among other scientific works published in 2013.
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