Autors:

CiteWeb id: 20090000113

CiteWeb score: 4391

Adipose tissue is a complex, essential, and highly active metabolic and endocrine organ. Besides adipocytes, adipose tissue contains connective tissue matrix, nerve tissue, stromovascular cells, and immune cells. Together these components function as an integrated unit. Adipose tissue not only responds to afferent signals from traditional hormone systems and the central nervous system but also expresses and secretes factors with important endocrine functions. These factors include leptin, other cytokines, adiponectin, complement components, plasminogen activator inhibitor-1, proteins of the renin-angiotensin system, and resistin. Adipose tissue is also a major site for metabolism of sex steroids and glucocorticoids. The important endocrine function of adipose tissue is emphasized by the adverse metabolic consequences of both adipose tissue excess and deficiency. A better understanding of the endocrine function of adipose tissue will likely lead to more rational therapy for these increasingly prevalent disorders. This review presents an overview of the endocrine functions of adipose tissue. (J Clin Endocrinol Metab 89: 2548–2556, 2004)

The publication "Adipose Tissue as an Endocrine Organ" is placed in the Top 10000 of the best publications in CiteWeb. Also in the category Biology it is included to the Top 1000. Additionally, the publicaiton "Adipose Tissue as an Endocrine Organ" is placed in the Top 1000 among other scientific works published in 2009.
Links to full text of the publication: