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Global QCD analysis of parton structure of the nucleon: CTEQ5 parton distributions ?

An up-to-date global QCD analysis of high energy lepton-hadron and hadron-hadron interactions is performed to better determine the gluon and quark parton distributions in the nucleon. Improved experimental data on inclusive jet production, in conjunction...

DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

We have identified and purified from HeLa cytosol a protein that induces DNA fragmentation in coincubated nuclei after it is activated by caspase-3. This protein, designated DNA Fragmentation Factor (DFF), is a heterodimer of 40 kDa and 45 kDa subunits....

Image Retrieval: Current Techniques, Promising Directions, and Open Issues

This paper provides a comprehensive survey of the technical achievements in the research area of image retrieval, especially content-based image retrieval, an area that has been so active and prosperous in the past few years. The survey includes 100+...

International experiences with the Hospital Anxiety and Depression Scale--a review of validation data and clinical results.

More than 200 published studies from most medical settings worldwide have reported experiences with the Hospital Anxiety and Depression Scale (HADS) which was specifically developed by Zigmond and Snaith for use with physically ill patients. Although...

Wireless sensor networks: a survey

This paper describes the concept of sensor networks which has been made viable by the convergence of micro-electro-mechanical systems technology, wireless communications and digital electronics. First, the sensing tasks and the potential sensor networks...

High-Resolution Inkjet Printing of All-Polymer Transistor Circuits

H. Sirringhaus, R. H. Friend, T. Shimoda, Michael Inbasekaran, W. W. Wu, E. P. Woo

Cortical Surface-Based Analysis II: Inflation, Flattening, and a Surface-Based Coordinate System

The surface of the human cerebral cortex is a highly folded sheet with the majority of its surface area buried within folds. As such, it is a difficult domain for computational as well as visualization purposes. We have therefore designed a set of procedures...

Guidelines on the management of valvular heart disease The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology

Helmut Baumgartner, Jeroen J. Bax, Eric G. Butchart, Robert A.E. Dion, Kasprzak Jd, Patrick Nataf, Pilar Tornos, Arnold Wenink

Principles of biomedical ethics

Tom L. Beauchamp, James F. Childress

Analysis of panel data

This book provides a comprehensive, coherent, and intuitive review of panel data methodologies that are useful for empirical analysis. Substantially revised from the second edition, it includes two new chapters on modeling cross-sectionally dependent...

On the implementation of an interior-point filter line-search algorithm for large-scale nonlinear programming

We present a primal-dual interior-point algorithm with a filter line-search method for nonlinear programming. Local and global convergence properties of this method were analyzed in previous work. Here we provide a comprehensive description of the algorithm,...

Elements of physical biology

Elements of physical biology

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-|[beta]|

Toshiyuki Nakagawa, Hong Zhu, Nobuhiro Morishima, En Li, Jin Xu, Bruce A. Yankner, Junying Yuan

Minimum probability of error for asynchronous Gaussian multiple-access channels

Consider a Gaussian multiple-access channel shared by K users who transmit asynchronously independent data streams by modulating a set of assigned signal waveforms. The uncoded probability of error achievable by optimum multiuser detectors is investigated....

Reporting physisorption data for gas/solid systems with special reference to the determination of surface area and porosity (Recommendations 1984)

Reporting physisorption data for gas/solid systems with special reference to the determination of surface area and porosity (Recommendations 1984)

Decimation of triangle meshes

William J. Schroeder, Jonathan A. Zarge, William E. Lorensen

BELIEF IN THE LAW OF SMALL NUMBERS

People have erroneous intuitions about the laws of chance. In particular, they regard a sample randomly drawn from a population as highly representative, that is, similar to the population in all essential characteristics.

Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

I. Introduction II. Role of Osteoblasts/Stromal Cells in Osteoclast Differentiation and Function A. Origin of osteoclasts B. Stimulation of osteoclast differentiation by osteoblasts/stromal cells C. Stimulation of osteoclast function by osteoblasts/stromal...

Generative programming: methods, tools, and applications

Krzysztof Czarnecki, Ulrich W. Eisenecker

Body-mass index and mortality in a prospective cohort of U.S. adults

Background Body-mass index (the weight in kilograms divided by the square of the height in meters) is known to be associated with overall mortality. We investigated the effects of age, race, sex, smoking status, and history of disease on the relation...

Secure routing in wireless sensor networks: attacks and countermeasures

We consider routing security in wireless sensor networks. Many sensor network routing protocols have been proposed, but none of them have been designed with security as a goal. We propose security goals for routing in sensor networks, show how attacks...

NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines

▪ Abstract Natural killer (NK) cells are populations of lymphocytes that can be activated to mediate significant levels of cytotoxic activity and produce high levels of certain cytokines and chemokines. NK cells respond to and are important in defense...

A beginner's guide to structural equation modeling

Randall E. Schumacker, Richard G. Lomax

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

Some cases of Alzheimer's disease are inherited as an autosomal dominant trait. Genetic linkage studies have mapped a locus (AD3) associated with susceptibility to a very aggressive form of Alzheimer's disease to chromosome 14q24.3. We have defined a...

A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans

The recently discovered orexigenic peptide ghrelin is produced primarily by the stomach and circulates in blood at levels that increase during prolonged fasting in rats. When administered to rodents at supraphysiological doses, ghrelin activates hypothalamic...

A model for p53-induced apoptosis

Kornelia Polyak, Yong Xia, Jay L. Zweier, Kenneth W. Kinzler, Bert Vogelstein

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

Makoto Kuro-o, Yutaka Matsumura, Hiroki Aizawa, Hiroshi Kawaguchi, Tatsuo Suga, Toshihiro Utsugi, Yoshio Ohyama, Masahiko Kurabayashi, Tadashi Kaname, Eisuke Kume, Hitoshi Iwasaki, Akihiro Iida, Takako Shiraki-Iida, Satoshi Nishikawa, Ryozo Nagai, Yo-ichi Nabeshima

Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

An estimated 170 million persons worldwide are infected with hepatitis C virus (HCV), a major cause of chronic liver disease. Despite increasing knowledge of genome structure and individual viral proteins, studies on virus replication and pathogenesis...

Making Democracy Work

Robert D. Putnam, Robert D. Putnam, Raffaella Y. Nonetti

Learning Deep Architectures for AI

Can machine learning deliver AI? Theoretical results, inspiration from the brain and cognition, as well as machine learning experiments suggest that in order to learn the kind of complicated functions that can represent high-level abstractions (e.g. in...

Toll-like receptors in innate immunity

Functional characterization of Toll-like receptors (TLRs) has established that innate immunity is askillfulsystemthat detectsinvasionofmicrobialpathogens.Recognition ofmicrobialcomponentsby TLRs initiates signal transduction pathways, which triggers expression...

Automata, Languages and Programming

Susanne Albers, Alberto Marchetti-Spaccamela, Yossi Matias, Sotiris Nikoletseas, Wolfgang Thomas

Modes of Foreign Entry: A Transaction Cost Analysis and Propositions

A “frontier issue” in international marketing is the appropriate choice of entry mode in foreign markets. The objective of this paper is to offer a transaction cost framework for investigating the entry mode decision. This framework provides 1) a...

Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI ☆

Quantitative-diffusion-tensor MRI consists of deriving and displaying parameters that resemble histological or physiological stains, i.e., that characterize intrinsic features of tissue microstructure and microdynamics. Specifically, these parameters...

Toward principles for the design of ontologies used for knowledge sharing

Recent work in Artificial Intelligence is exploring the use of formal ontologies as a way of specifying content-specific agreements for the sharing and reuse of knowledge among software entities. We take an engineering perspective on the development of...

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